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巨大心脏黏液瘤伴血小板减少患者:二者是否存在病理生理学联系?(附病例报告)

Giant cardiac myxoma in a patient with thrombocytopenia: is there a physiopathologic link? (a case report).

机构信息

Department of Cardiology, Military Hospital of Tunis, Tunis, Tunisia.

出版信息

Pan Afr Med J. 2020 Dec 16;37:348. doi: 10.11604/pamj.2020.37.348.26109. eCollection 2020.

DOI:10.11604/pamj.2020.37.348.26109
PMID:33738036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7934194/
Abstract

Atrial myxoma is the most common primary cardiac tumor. We report the case of left atrium myxoma accompanied by severe thrombocytopenia in a 72-years-old woman. The thrombocytopenia has been discovered 5 years ago, it was explored, no obvious cause was found, the diagnosis of idiopathic thrombocytopenia was retained based on clinical and paraclinical arguments, corticosteroid treatment was ineffective and platelet count remains low. Complete surgical excision of the mass was performed. Platelet count was gradually increased to reach 95 103/µl after 6 months postoperatively. In this report, we highlight that thrombocytopenia might be one rare hematological manifestation of myxoma but need more cases for support. By illustrating this association, we hope to facilitate an earlier diagnosis of cardiac myxoma to treat and avoid complications of both thrombocytopenia and myxoma.

摘要

心房黏液瘤是最常见的原发性心脏肿瘤。我们报告了一例 72 岁女性左心房黏液瘤合并严重血小板减少症的病例。5 年前发现血小板减少症,进行了检查,未发现明显病因,根据临床和辅助检查结果保留特发性血小板减少症的诊断,皮质类固醇治疗无效,血小板计数仍然较低。行肿块完整切除术。术后 6 个月血小板计数逐渐升高至 95×103/µl。本报告强调血小板减少症可能是黏液瘤的一种罕见血液学表现,但需要更多病例支持。通过阐明这种关联,我们希望能够更早诊断心脏黏液瘤,进行治疗并避免血小板减少症和黏液瘤的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/3335ef714cda/PAMJ-37-348-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/d3f34a35ccf3/PAMJ-37-348-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/b621970b0fe5/PAMJ-37-348-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/083550b48f67/PAMJ-37-348-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/d9e496d8dcf4/PAMJ-37-348-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/3335ef714cda/PAMJ-37-348-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/d3f34a35ccf3/PAMJ-37-348-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/b621970b0fe5/PAMJ-37-348-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/083550b48f67/PAMJ-37-348-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/d9e496d8dcf4/PAMJ-37-348-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aaf/7934194/3335ef714cda/PAMJ-37-348-g005.jpg

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Complete remission of immune thrombocytopenia in a 30-year old woman after excision of a right atrial myxoma.一名30岁女性右心房黏液瘤切除术后免疫性血小板减少症完全缓解。
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