Department of Cardiology, National Heart Centre Singapore, Singapore.
Department of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore.
Singapore Med J. 2021 Apr;62(4):195-198. doi: 10.11622/smedj.2020041. Epub 2020 Mar 31.
Cardiac myxoma is the most common cardiac tumour. In this study, we summarise our 17-year experience with the clinical presentation of cardiac myxoma at National Heart Centre Singapore, Singapore.
Between January 2000 and December 2016, retrospective data was reviewed for all consecutive patients who underwent surgical resection of cardiac myxoma. Patients' clinical characteristics were reviewed and described.
A total of 67 (18 male, 49 female; mean age 53.1 ± 13.5 years) patients underwent cardiac myxoma resection. There were 19 (28.4%) patients with asymptomatic cardiac myxoma. There were no significant differences in gender; body habitus and myxoma size; and haemoglobin, white blood cell or platelet counts between patients with symptomatic and asymptomatic myxoma. However, the number of asymptomatic cardiac myxomas seemed to follow an increasing trend from 19.4% (period 2000-2008) to 36.1% (period 2009-2016), suggestive of an 'era effect'.
In our study, a majority of patients were women, with a wide age range of 18-78 years. The diagnosis of asymptomatic cardiac myxoma was present in 28.4% of patients, with an increasing trend for incidence over the years. This is possibly due to increased opportunistic screening (with electrocardiography and clinical examination) as well as higher usage of medical imaging.
心脏黏液瘤是最常见的心脏肿瘤。本研究总结了新加坡国家心脏中心 17 年来心脏黏液瘤的临床表现。
2000 年 1 月至 2016 年 12 月,回顾性分析连续接受心脏黏液瘤手术切除的所有患者的回顾性数据。对患者的临床特征进行了回顾和描述。
共 67 例(18 例男性,49 例女性;平均年龄 53.1 ± 13.5 岁)患者接受了心脏黏液瘤切除术。有 19 例(28.4%)无症状心脏黏液瘤患者。有症状和无症状黏液瘤患者的性别、体型和黏液瘤大小、血红蛋白、白细胞或血小板计数无显著差异。然而,无症状心脏黏液瘤的数量似乎呈上升趋势,从 2000-2008 年的 19.4%上升到 2009-2016 年的 36.1%,提示存在“时代效应”。
在我们的研究中,大多数患者为女性,年龄范围为 18-78 岁。无症状心脏黏液瘤的诊断见于 28.4%的患者,其发病率呈逐年上升趋势。这可能是由于机会性筛查(心电图和临床检查)的增加以及医学影像学的广泛应用。