Nuesi Ronaldo, Swaminathan Swarup S
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA.
Curr Ophthalmol Rep. 2020 Sep;8(3):111-119. doi: 10.1007/s40135-020-00235-z. Epub 2020 Jun 4.
To summarize the available literature on retinal imaging metrics in the context of intravitreal injections in glaucomatous and non-glaucomatous eyes.
The retinal nerve fiber layer (RNFL) in injected non-glaucomatous eyes appears to thin at a similar rate to uninjected fellow eyes. A total of four studies evaluating RNFL thinning in injected glaucomatous eyes yielded mixed results, with more recent longitudinal investigations suggesting a potential association. The ganglion cell-inner plexiform layer is also being studied as a potential endpoint in both glaucomatous and non-glaucomatous eyes following intravitreal injections.
总结在青光眼和非青光眼眼中玻璃体内注射情况下视网膜成像指标的现有文献。
注射过的非青光眼眼中的视网膜神经纤维层(RNFL)变薄速度似乎与未注射的对侧眼相似。共有四项评估注射过的青光眼眼中RNFL变薄情况的研究结果不一,而最近的纵向研究表明可能存在关联。神经节细胞 - 内丛状层也正在作为玻璃体内注射后青光眼和非青光眼眼的潜在终点进行研究。