Talanas Giuseppe, Corda Giulia, Parodi Guido, Portoghese Michele
Department of Cardiology, Sassari University Hospital, Via Enrico De Nicola, 07100 Sassari, Italy.
Eur Heart J Case Rep. 2021 Feb 22;5(2):ytab052. doi: 10.1093/ehjcr/ytab052. eCollection 2021 Feb.
Left main (LM) coronary atresia (LMCA) is a rare coronary anomaly where the LM is congenitally absent and a variable clinical spectrum can follow. The diagnosis of LMCA is generally made in youth because of the development of symptoms, but very rarely in adulthood. In symptomatic patients, surgical revascularization is recommended, whereas, in asymptomatic patients with LMCA and without inducible myocardial ischaemia, preventive surgical treatment is controversial.
A 58-year-old male patient with aortic ectasia detected during an echocardiogram performed to evaluate a hypertension-related preclinical cardiac damage and, due to this finding, an echocardiographic follow-up was suggested. Three years later, he was admitted to undergo coronary angiography (CA) after the computed tomography finding of a suspected occlusion of the LM with collateral circulation from right coronary artery (RCA) to left anterior descending and circumflex arteries. CA confirmed an LMCA and the RCA provided blood supply to the left coronary artery through collaterals whose calibre was similar to that of the target left-sided vessels. No obstructive coronary artery disease was detected. In order to detect potential myocardial ischaemia, a technetium-tetrofosmin cardiac single-photon emission computed tomography during maximal exercise-stress test was performed and it did not show a perfusion defect. Medical management with scheduled follow-up visits was deemed to be the best therapeutic option.
LMCA is a rare anomaly where LM is absent and the RCA provides collateral circulation for left coronary artery. In asymptomatic patients, preventive surgical treatment is controversial.
左主干(LM)冠状动脉闭锁(LMCA)是一种罕见的冠状动脉异常,即左主干先天性缺失,随后可能出现多种临床表现。LMCA的诊断通常在年轻时因症状出现而做出,但在成年期非常罕见。对于有症状的患者,建议进行手术血运重建,而对于无症状的LMCA患者且无诱发性心肌缺血,预防性手术治疗存在争议。
一名58岁男性患者,在为评估高血压相关的临床前心脏损害而进行的超声心动图检查中发现主动脉扩张,基于这一发现,建议进行超声心动图随访。三年后,计算机断层扫描发现疑似LM闭塞且右冠状动脉(RCA)向左前降支和回旋支有侧支循环,随后他入院接受冠状动脉造影(CA)。CA证实为LMCA,RCA通过侧支为左冠状动脉供血,侧支口径与左侧目标血管相似。未检测到阻塞性冠状动脉疾病。为检测潜在的心肌缺血,在最大运动负荷试验期间进行了锝-四甲基异腈心脏单光子发射计算机断层扫描,结果未显示灌注缺损。认为最佳治疗选择是进行药物治疗并定期随访。
LMCA是一种罕见的异常,即左主干缺失,RCA为左冠状动脉提供侧支循环。对于无症状患者,预防性手术治疗存在争议。