Laboratoire de Psychologie des Pays de la Loire, Nantes Université, Univ Angers, Nantes, France.
Unité de Gériatrie, Centre Hospitalier de Tourcoing, Tourcoing, France.
Neurocase. 2021 Apr;27(2):155-159. doi: 10.1080/13554794.2021.1902539. Epub 2021 Mar 19.
We investigate whether retrograde-amnesia can be indexed with pupil activity. We present the case of L, 19-year-old, without neurological or psychiatric disorders except for retrograde-amnesia. We invited L to retrieve retrograde and anterograde memories while his pupil size was monitering with eye-tracking glasses. Results demonstrated impaired retrograde retrieval but successful anterograde retrieval in L. He also attributed lower emotional value and visual imagery to his retrograde compared to his anterograde memories. Critically, smaller pupils were observed during retrograde than during anterograde retrieval. Our study provides the first evidence on the value of pupillometry as a potential physiological marker of amnesia.
我们研究了逆行性遗忘是否可以通过瞳孔活动来标记。我们呈现了一个案例，案例中的 L 是一位 19 岁的年轻人，除了逆行性遗忘，没有任何神经或精神疾病。我们邀请 L 在使用眼动追踪眼镜监测瞳孔大小的同时，检索逆行性和顺行性记忆。结果表明，L 的逆行性检索受损，但顺行性检索成功。他还认为，与顺行性记忆相比，他的逆行性记忆的情绪价值和视觉形象较低。重要的是，在逆行性检索期间观察到的瞳孔较小，而在顺行性检索期间观察到的瞳孔较大。我们的研究提供了第一个证据，证明瞳孔测量作为遗忘的潜在生理标志物的价值。
