Laboratoire de psychologie des Pays de la Loire, Nantes Université, Univ Angers, LPPL, Nantes, France.
Clinical Gerontology Department, CHU Nantes, Nantes, France.
Neurocase. 2022 Jun;28(3):270-275. doi: 10.1080/13554794.2022.2094809. Epub 2022 Jun 29.
We investigated whether pupil size can variate with the intensity of cognitive processing in patients with behavioral-variant-Frontotemporal-Dementia (bvFTD). We invited five bvFTD participants and 21 controls to perform forward spans and backward spans, and, in a control condition, to count aloud. We recorded pupil activity using eye-tracking-glasses during the spans and control condition. Analysis demonstrated larger pupil sizes during backward spans than during forward spans, and larger pupil sizes during forward spans than during counting in both bvFTD and control participants. These findings demonstrate how increased cognitive load triggers increased pupil size and how this connection is maintained in bvFTD.
我们研究了行为变异额颞叶痴呆（bvFTD）患者的瞳孔大小是否会随认知处理强度而变化。我们邀请了五名 bvFTD 参与者和 21 名对照组参加前向跨度和后向跨度任务，并在控制条件下大声数数。我们在跨度和控制条件期间使用眼动跟踪眼镜记录瞳孔活动。分析表明，后向跨度期间的瞳孔比前向跨度大，前向跨度期间的瞳孔比计数时的瞳孔大，bvFTD 患者和对照组参与者都是如此。这些发现表明，认知负荷增加如何引发瞳孔增大，以及这种联系在 bvFTD 中是如何维持的。
