Makerere University Center for Health and Population Research, Kampala, Uganda.
Iganga-Mayuge Health and Demographic Surveillance Site, Iganga, Uganda.
PLoS One. 2021 Mar 19;16(3):e0248966. doi: 10.1371/journal.pone.0248966. eCollection 2021.
There is a dearth of studies assessing non-communicable disease (NCD) mortality within population-based settings in Uganda. We assessed mortality due to major NCDs among persons ≥ 30 years in Eastern Uganda from 2010 to 2016.
The study was carried out at the Iganga-Mayuge health and demographic surveillance site in the Iganga and Mayuge districts of Eastern Uganda. Information on cause of death was obtained through verbal autopsies using a structured questionnaire to conduct face-face interviews with carers or close relatives of the deceased. Physicians assigned likely cause of death using ICD-10 codes. Age-adjusted mortality rates were calculated using direct method, with the average population across the seven years of the study (2010 to 2016) as the standard. Age categories of 30-40, 41-50, 51-60, 61-70, and ≥ 71 years were used for standardization.
A total of 1,210 deaths among persons ≥ 30 years old were reported from 2010 to 2016 (50.7% among women). Approximately 53% of all deaths were due to non-communicable diseases, 31.8% due to communicable diseases, 8.2% due to injuries, and 7% due to maternal-related deaths or undetermined causes. Cardiovascular diseases accounted for the largest proportion of NCD deaths in each year, and women had substantially higher cardiovascular disease mortality rates compared to men. Conversely, women had lower diabetes mortality rates than men for five of the seven years examined.
Non-communicable diseases are major causes of death among adults in Iganga and Mayuge; and cardiovascular diseases and diabetes are leading causes of NCD deaths. Efforts are needed to tackle NCD risk factors and provide NCD care to reduce associated burden and premature mortality.
乌干达缺乏基于人群的非传染性疾病(NCD)死亡率研究。我们评估了 2010 年至 2016 年期间乌干达东部 30 岁以上人群的主要 NCD 死亡率。
该研究在乌干达东部伊甘加和马尤盖地区的伊甘加-马尤盖卫生和人口监测点进行。通过使用结构化问卷进行面对面访谈,从死者的照顾者或近亲那里获取死因信息。医生使用 ICD-10 代码来确定可能的死因。使用直接法计算年龄调整死亡率,以研究期间(2010 年至 2016 年)的平均人口为标准。使用年龄组 30-40、41-50、51-60、61-70 和≥71 岁进行标准化。
2010 年至 2016 年期间,报告了 1210 例 30 岁以上人群死亡(女性占 50.7%)。所有死亡中约有 53%归因于非传染性疾病,31.8%归因于传染性疾病,8.2%归因于伤害,7%归因于与母亲有关的死亡或原因不明。心血管疾病占每年 NCD 死亡的最大比例,女性的心血管疾病死亡率明显高于男性。相反,在研究的七年中有五年,女性的糖尿病死亡率低于男性。
非传染性疾病是伊甘加和马尤盖成年人死亡的主要原因;心血管疾病和糖尿病是非传染性疾病死亡的主要原因。需要努力解决非传染性疾病危险因素,并提供非传染性疾病护理,以减轻相关负担和过早死亡。