Aringer Martin, Schneider Matthias
Bereich Rheumatologie, Medizinische Klinik und Poliklinik III und UniversitätsCentrum für Autoimmun- und Rheumatische Erkrankungen (UCARE), Universitätsklinikum und Medizinische Fakultät Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307, Dresden, Deutschland.
Poliklinik und Funktionsbereich für Rheumatologie und Hiller Forschungszentrum für Rheumatologie, Universitätsklinikum Düsseldorf, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Deutschland.
Hautarzt. 2021 Apr;72(4):337-348. doi: 10.1007/s00105-021-04794-5.
Systemic lupus erythematosus (SLE) is a highly variable disease driven by the tendency to form very different types of antibody. This sometimes leads to an exaggerated respect for the complexity of the disease symptoms and to uncertainty in dealing with affected patients; however, nowadays the most important measures in the diagnosis and management of the disease can be broken down to a manageable extent. In this respect, the new recommendations of the European League Against Rheumatism (EULAR) on SLE and the recommendations on lupus nephritis jointly developed by EULAR and the European Renal Association/European Dialysis and Transplant Association (ERA/EDTA) are helpful, as are the new classification criteria from EULAR and the American College of Rheumatology (ACR). In this article the core points of these publications are summarized and contemporary SLE management is presented. As a rule, SLE can be effectively treated when managed in this way.
系统性红斑狼疮（SLE）是一种高度可变的疾病，由形成非常不同类型抗体的倾向所驱动。这有时会导致对疾病症状复杂性的过度重视以及在治疗受影响患者时的不确定性；然而，如今该疾病诊断和管理中的最重要措施在一定程度上可以细化为可管理的内容。在这方面，欧洲抗风湿病联盟（EULAR）关于SLE的新建议以及EULAR与欧洲肾脏协会/欧洲透析和移植协会（ERA/EDTA）联合制定的狼疮性肾炎建议很有帮助，EULAR和美国风湿病学会（ACR）的新分类标准也很有帮助。本文总结了这些出版物的核心要点，并介绍了当代SLE的管理方法。通常，以这种方式管理SLE可以得到有效治疗。
