Federal University of Pelotas, School of Physical Education, Pelotas, Brazil.
Federal University of Pelotas, School of Physical Education, Pelotas, Brazil.
Epilepsy Behav. 2021 Apr;117:107904. doi: 10.1016/j.yebeh.2021.107904. Epub 2021 Mar 16.
To evaluate the effects of an exercise program on the health of people with epilepsy (PWE) and seizure frequency. A randomized clinical trial was carried out in Pelotas/Brazil. Recruitment was conducted through social media, in local press, and Public Health System facilities. The intervention program was performed at the gym of the Physical Education School/Federal University of Pelotas. A total of 21 people, aged 18-60 years, diagnosed with epilepsy and who were not engaged in systematic physical exercise in the last three months were divided into two groups: (1) exercise (EG) - 12 weeks of a structured physical exercise program; (2) control (CG) - no exercise and maintenance of usual activities. The allocation rate 1:1 was used. The exercise program consisted of two 60-min weekly sessions including warm-up (5-min), aerobic training (15-25 min at 14-17 on Borg scale), resistance training (2-3 sets, 10-15 repetitions), and stretching. Sociodemographic, clinical and health variables (frequency and number of seizures, quality of life, depression, anxiety, and side effects), anthropometrics (weight, height, hip and waist circumferences), cardiorespiratory fitness (VO), and strength (dynamometry) were measured at baseline and after the 12-week intervention. Generalized Estimating Equations (GEE) and Bonferroni posthoc tests were used for the comparison between moments and groups. Eleven participants were randomized to EG and 10 to CG. One EG participant did not complete the study. There was a reduction in frequency of epileptic seizures during the 3-month intervention period in EG (p = 0.010) with no improvement in CG. Improvement in quality of life (p = 0.004), stress levels (p = 0.017) and physical fitness (p = 0.017) were also observed in the EG compared to CG. A structured physical exercise program improved overall health of PWE and decreased seizure frequency.
评估运动方案对癫痫患者（PWE）健康和癫痫发作频率的影响。在巴西佩洛塔斯进行了一项随机临床试验。通过社交媒体、当地媒体和公共卫生系统设施进行招募。干预方案在佩洛塔斯联邦大学体育教育学校的健身房进行。共有 21 名年龄在 18-60 岁之间、被诊断患有癫痫且在过去三个月内没有进行系统体育锻炼的人被分为两组：（1）运动（EG）- 12 周的结构化体育锻炼方案；（2）对照组（CG）-不运动并维持日常活动。使用 1:1 的分配率。运动方案包括每周两次、每次 60 分钟的课程，包括热身（5 分钟）、有氧运动（15-25 分钟，Borg 量表 14-17 级）、抗阻训练（2-3 组，10-15 次重复）和伸展运动。在基线和 12 周干预后测量社会人口统计学、临床和健康变量（癫痫发作频率和次数、生活质量、抑郁、焦虑和副作用）、人体测量学（体重、身高、臀围和腰围）、心肺适能（VO）和力量（握力计）。使用广义估计方程（GEE）和 Bonferroni 事后检验比较组间和组内的差异。11 名参与者被随机分配到 EG，10 名参与者被分配到 CG。一名 EG 参与者未完成研究。在 EG 中，癫痫发作频率在 3 个月的干预期间有所降低（p=0.010），而 CG 中没有改善。与 CG 相比，EG 还观察到生活质量（p=0.004）、压力水平（p=0.017）和身体适应性（p=0.017）的改善。结构化的体育锻炼方案改善了癫痫患者的整体健康状况并降低了癫痫发作频率。
