Department of Gastrointestinal Surgery, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Department of Gastrointestinal Surgery, Sichuan Cancer Hospital, Chengdu, China.
BMC Surg. 2021 Mar 19;21(1):140. doi: 10.1186/s12893-021-01153-y.
Proximal gastrectomy with double-tract reconstruction (DTR) has been used for upper third gastric cancer as a function-preserving procedure. However, the safety and feasibility of laparoscopic proximal gastrectomy (LPG) with DTR remain uncertain. This study compared open proximal gastrectomy (OPG) with DTR and LPG with DTR for proximal gastric cancer.
Sixty-four patients who had undergone OPG with DTR and forty-six patients who had undergone LPG with DTR were enrolled in this case-control study. The clinical characteristics, surgical outcomes and postoperative nutrition index were analysed retrospectively.
The operation time was significantly longer in the LGP group than in the OPG group (258.3 min vs 205.8 min; p = 0.00). However, the time to first flatus and postoperative hospital stay were shorter in the LPG group [4.0 days vs 3.5 days (p = 0.00) and 10.6 days vs 9.2 days (p = 0.001), respectively]. No significant difference was found between the two groups in the number of retrieved lymph nodes, complications or reflux oesophagitis. The nutrition status was assessed using the haemoglobin, albumin, prealbumin and weight levels from pre-operation to six months after surgery. No significant difference was found between the groups.
LPG with DTR can be safely performed for proximal gastric cancer patients by experienced surgeons.
双途径重建(DTR)的近端胃切除术已被用于治疗胃上部三分之一的癌症,作为一种保留功能的手术。然而,腹腔镜近端胃切除术(LPG)联合 DTR 的安全性和可行性仍不确定。本研究比较了开放近端胃切除术(OPG)联合 DTR 与 LPG 联合 DTR 治疗近端胃癌的效果。
本病例对照研究共纳入 64 例行 OPG 联合 DTR 和 46 例行 LPG 联合 DTR 的患者。回顾性分析了两组患者的临床特征、手术结果和术后营养指标。
LPG 组的手术时间明显长于 OPG 组(258.3 分钟比 205.8 分钟;p=0.00)。然而,LPG 组的首次肛门排气时间和术后住院时间更短[4.0 天比 3.5 天(p=0.00)和 10.6 天比 9.2 天(p=0.001)]。两组患者的淋巴结检出数、并发症或反流性食管炎发生率无显著差异。通过血红蛋白、白蛋白、前白蛋白和体重水平来评估营养状况,从术前到术后 6 个月,两组间无显著差异。
经验丰富的外科医生可以安全地为近端胃癌患者实施 LPG 联合 DTR。