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前列腺癌局部放疗后的挽救性前列腺切除术。

Salvage radical prostatectomy after local radiotherapy in prostate cancer.

机构信息

Department of Urology, Urooncology and Robot Assisted Surgery, University Hospital of Cologne, Cologne, Germany.

出版信息

Curr Opin Urol. 2021 May 1;31(3):194-198. doi: 10.1097/MOU.0000000000000873.

Abstract

PURPOSE OF REVIEW

Salvage surgeries are rarely offered and performed in prostate cancer except for isolated lymph node metastases. Meanwhile, data are sufficient that salvage radical prostatectomy is recommended by the guidelines. In the following review, we focus on different treatment strategies comparing open and DaVinci laparoscopic approach with regard to functional and oncologic outcome. Of further interest are palliative surgeries.

RECENT FINDINGS

Salvage radical prostatectomy is mainly performed in high volume centres. Data are increasing on minimal invasive surgery, although data on functional outcome are conflicting. As patients with prostate cancer have longer life expectancy even in metastasized disease, the possibility of developing symptomatic progression increases as well. We need to be aware that the confrontation with symptomatic prostate cancer patients will be more frequent in the future and that there are surgical approaches to palliate these patients sufficiently.

SUMMARY

Data on minimal invasive salvage radical prostatectomy are getting more valid and are an option in experienced centres. Salvage radical prostatectomy is a definitive curative option for the patients. To avoid local progression, palliative local surgeries need to be discussed with the patients.

摘要

目的综述

前列腺癌除孤立性淋巴结转移外,很少进行挽救性手术。同时,有足够的数据表明,指南推荐进行挽救性根治性前列腺切除术。在以下综述中,我们关注了开放和达芬奇腹腔镜手术在功能和肿瘤学结果方面的不同治疗策略。进一步关注的是姑息性手术。

最近的发现

挽救性根治性前列腺切除术主要在高容量中心进行。微创数据在增加,尽管功能结果的数据存在冲突。由于患有前列腺癌的患者即使在转移疾病中也有更长的预期寿命,因此发生症状进展的可能性也会增加。我们需要意识到,未来会有更多患有症状性前列腺癌的患者需要面对,并且有足够的手术方法来缓解这些患者的症状。

总结

微创挽救性根治性前列腺切除术的数据越来越有效,并且是经验丰富的中心的一个选择。挽救性根治性前列腺切除术是患者的明确治愈选择。为了避免局部进展,需要与患者讨论姑息性局部手术。

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