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白种青少年慢性免疫性血小板减少症后发生自身免疫性胰腺炎。

Occurrence of autoimmune pancreatitis after chronic immune thrombocytopenia in a Caucasian adolescent.

机构信息

Department of Pediatrics and Adolescent Medicine, St. Anna Children's Hospital, Medical University Vienna, Kinderspitalgasse 6, 1090, Vienna, Austria.

Department of Pediatric Nephrology and Gastroenterology, Medical University Vienna, Vienna, Austria.

出版信息

Clin J Gastroenterol. 2021 Jun;14(3):918-922. doi: 10.1007/s12328-021-01383-w. Epub 2021 Mar 20.

Abstract

Autoimmune pancreatitis is a rare, distinct and increasingly recognized form of chronic inflammatory pancreatic disease secondary to an underlying autoimmune mechanism. We report on a 14-year-old boy who developed autoimmune pancreatitis, while he was under treatment with eltrombopag for chronic immune thrombocytopenia. Therapy with corticosteroids resulted in complete remission of both. This is the first report on the co-occurrence of autoimmune pancreatitis and chronic immune thrombocytopenia in childhood, and clinicians should be aware of this rare association, because early diagnosis and therapy of autoimmune pancreatitis may prevent severe complications.

摘要

自身免疫性胰腺炎是一种罕见的、独特的、日益被认识的慢性炎症性胰腺疾病,继发于潜在的自身免疫机制。我们报告了一例 14 岁男孩,在接受依鲁替尼治疗慢性免疫性血小板减少症时发生了自身免疫性胰腺炎。皮质类固醇治疗导致两种疾病完全缓解。这是首例儿童中自身免疫性胰腺炎和慢性免疫性血小板减少症同时发生的报道,临床医生应该意识到这种罕见的关联,因为早期诊断和治疗自身免疫性胰腺炎可能预防严重并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1095/8154769/c97c3fe1854f/12328_2021_1383_Fig1_HTML.jpg

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