Willis Kurt, Bullock Martin, Rigby Matthew H
Faculty of Medicine, Dalhousie University, Halifax, Canada.
Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
Int J Surg Case Rep. 2021 Apr;81:105750. doi: 10.1016/j.ijscr.2021.105750. Epub 2021 Mar 13.
Secretory Carcinoma is a recently discovered head and neck tumour. Surgical resection is generally the first line of treatment with neck dissection, radiation, and chemotherapy decided based on clinical, radiological, and histological parameters. We present a case of a Secretory Carcinoma presenting in the maxillary and ethmoid sinuses.
A 39-year-old male presented with left nasal obstruction and chronic rhinosinusitis beginning after surgical repair of the mandible and maxilla due to facial trauma. A CT scan of the head showed soft tissue density in the left maxillary sinus extending through the ethmoid sinus and posterior nasal cavity. Functional endoscopic sinus surgery (FESS) was performed to remove the obstructing lesion. Biopsy was analysed and the main differential diagnosis was between a non-intestinal type adenocarcinoma of nasal origin and a salivary carcinoma.
To our knowledge, there have only been two cases of Secretory Carcinoma reported in the sinuses: one case in the ethmoid sinus and the other in the maxillary sinus. This is the first to report follow up at 1 year.
Both MRI and exam showed no evidence of recurrent disease at one year follow up. This report aims to further the understanding of Secretory Carcinoma tumours in the sinuses. Our report could be used to further understand diagnostic criteria for Secretory Carcinoma in the sinuses as well as treatment outcomes for surgical resection without adjuvant treatment.
分泌性癌是一种最近发现的头颈部肿瘤。手术切除通常是一线治疗方法,根据临床、影像学和组织学参数决定是否进行颈部清扫、放疗和化疗。我们报告一例发生于上颌窦和筛窦的分泌性癌病例。
一名39岁男性,因面部创伤接受下颌骨和上颌骨手术修复后,出现左侧鼻塞和慢性鼻窦炎。头部CT扫描显示左侧上颌窦软组织密度影,延伸至筛窦和后鼻腔。进行了功能性鼻内镜鼻窦手术(FESS)以切除阻塞性病变。对活检组织进行分析,主要鉴别诊断为鼻源性非肠型腺癌和涎腺癌。
据我们所知,仅报道过两例鼻窦分泌性癌病例:一例发生于筛窦,另一例发生于上颌窦。这是首例报告1年随访情况的病例。
1年随访时,MRI检查和体格检查均未发现疾病复发迹象。本报告旨在加深对鼻窦分泌性癌肿瘤的认识。我们的报告可用于进一步了解鼻窦分泌性癌的诊断标准以及无辅助治疗情况下手术切除的治疗效果。