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色素细胞和图案的演化:硬骨鱼类的最新研究进展。

Evolution of pigment cells and patterns: recent insights from teleost fishes.

机构信息

Department of Biology, Department of Cell Biology, University of Virginia, Charlottesville, VA 22903, United States.

出版信息

Curr Opin Genet Dev. 2021 Aug;69:88-96. doi: 10.1016/j.gde.2021.02.006. Epub 2021 Mar 17.

Abstract

Skin pigment patterns of vertebrates are stunningly diverse, and nowhere more so than in teleost fishes. Several species, including relatives of zebrafish, recently evolved cichlid fishes of East Africa, clownfishes, deep sea fishes, and others are providing insights into pigment pattern evolution. This overview describes recent advances in understanding periodic patterns, like stripes and spots, the loss of patterns, and the role of cell-type diversification in generating pigmentation phenotypes. Advances in this area are being facilitated by the application of modern methods of gene editing, genomics, computational analysis, and other approaches to non-traditional model organisms having interesting pigmentary phenotypes. Several topics worthy of future attention are outlined as well.

摘要

脊椎动物的皮肤色素模式变化多样,其中以硬骨鱼类最为显著。包括斑马鱼近亲在内的一些鱼类、东非慈鲷鱼、小丑鱼、深海鱼类等,为人们了解色素模式进化提供了线索。本文概述了近年来在周期性模式(如条纹和斑点)、模式缺失以及细胞类型多样化在产生色素表型中的作用等方面的研究进展。该领域的进展得益于现代基因编辑方法、基因组学、计算分析以及其他方法在具有有趣色素表型的非传统模式生物中的应用。本文还概述了几个值得未来关注的主题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32e/8364858/fc0bbd9b25f2/nihms-1675968-f0001.jpg

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