Department of Otolaryngology-Head and Neck Surgery, Tufts Medical Center, Box #850, 800 Washington Street, Boston, MA 02111, USA.
Department of Otolaryngology-Head and Neck Surgery, University of Arizona College of Medicine, 1501 North Campbell Avenue, Room 5401, Tucson, AZ 85724, USA.
Otolaryngol Clin North Am. 2021 Apr;54(2):247-257. doi: 10.1016/j.otc.2020.11.001.
Cutaneous malignancy is becoming an increasing public health burden in terms of morbidity and cost, associated with changing environmental exposures and increased longevity of the general and the immunosuppressed population. Yet the understanding of the scope of this problem is hindered by lack of robust registries for nonmelanoma skin cancer. The risk factor responsible for most of these cancers, exposure to ultraviolet radiation, can be mitigated. However, greater consensus is necessary to enact effective prevention and screening programs. New developments, including identification of biomarkers and use of artificial intelligence, show promise for targeting screening efforts.
皮肤恶性肿瘤在发病率和成本方面给公共健康带来的负担日益加重，这与环境暴露的变化以及普通人群和免疫抑制人群寿命的延长有关。然而，由于缺乏针对非黑色素瘤皮肤癌的强大登记处，对这一问题的理解受到阻碍。导致大多数此类癌症的危险因素是紫外线辐射暴露，可以减轻这种风险。但是，需要达成更大共识，以制定有效的预防和筛查计划。新的发展，包括生物标志物的鉴定和人工智能的使用，为有针对性的筛查工作带来了希望。
