Department of Therapy, University Children's Hospital of Basel, Basel, Switzerland; Department of Sport, Exercise and Health, University of Basel, Birsstrasse 320 B, 4052, Basel, Switzerland.
University Medical Library, University of Basel, Spiegelgasse 5, 4051, Basel, Switzerland.
Phys Ther Sport. 2021 May;49:178-187. doi: 10.1016/j.ptsp.2021.03.002. Epub 2021 Mar 9.
Osgood-Schlatter disease (OSD) is a sport- and growth-associated knee pathology with locally painful alterations around the tibial tuberosity apophysis. Up to 10% of adolescents are affected by OSD. Treatment is predominantly conservative. The aims of this systematic review are to comprehensively identify conservative treatment options for OSD, compare their effectiveness in selected outcomes, and describe potential research gaps.
A systematic literature search was conducted using CENTRAL, CINAHL, EMBASE, MEDLINE, and PEDro databases. In addition, ongoing and unpublished clinical studies, dissertations, and other grey literature on OSD were searched. We also systematically retrieved review articles for extraction of treatment recommendations.
Of 767 identified studies, thirteen were included, comprising only two randomised controlled trials (RCTs). The included studies were published from 1948 to 2019 and included 747 patients with 937 affected knees. Study quality was poor to moderate. In addition to the studies, 15 review articles were included, among which the most prevalent treatment recommendations were compiled.
Certain therapeutic approaches, such as stretching, have apparent efficacy, but no RCT comparing specific exercises with sham or usual-care treatment exists. Carefully controlled studies on well-described treatment approaches are needed to establish which conservative treatment options are most effective for patients with OSD.
奥萨格-施莱特尔病（OSD）是一种与运动和生长相关的膝关节疾病，其特征为胫骨结节骨骺端局部疼痛改变。多达 10%的青少年受到 OSD 的影响。治疗主要是保守的。本系统评价的目的是全面确定 OSD 的保守治疗选择，比较它们在选定结局方面的有效性，并描述潜在的研究空白。
使用 CENTRAL、CINAHL、EMBASE、MEDLINE 和 PEDro 数据库进行系统文献检索。此外，还对 OSD 的正在进行和未发表的临床研究、学位论文和其他灰色文献进行了检索。我们还系统地检索了综述文章，以提取治疗建议。
在 767 项已确定的研究中，有 13 项被纳入，其中仅包括 2 项随机对照试验（RCT）。纳入的研究发表于 1948 年至 2019 年，共纳入 747 例患者，937 例膝部受累。研究质量为差至中等。除了这些研究，还纳入了 15 篇综述文章，其中最常见的治疗建议被汇编在一起。
某些治疗方法，如伸展运动，具有明显的疗效，但没有 RCT 比较特定的运动与假治疗或常规治疗。需要进行精心控制的研究，以确定哪些保守治疗方法对 OSD 患者最有效。
