Konstantinova I M, Kozlov Iu V, Kulichkova V A, Petukhova O A, Kurmanova A G
Mol Biol (Mosk). 1988 Jan-Feb;22(1):209-16.
Double-stranded segments (c-ds) have been studied in the poly(A)+ cytoplasmic rat liver RNA. Duplexes about 40 base pairs long have been shown to be of intermolecular character and originate from the interaction between ss-RNA and complementary regions of the poly(A)-containing RNA molecules. Shorter ds-sequences are, mainly, of intramolecular nature. Double-stranded sequences of different length differ also in their oligonucleotide composition, according to fingerprint analysis data. Under the action of cortisone, only several kinds of double-stranded sequences have been demonstrated to increase in the population of cytoplasmic poly(A)+RNA. The function of ds-regions in the hormonal regulation of gene expression is suggested.
已对大鼠肝脏细胞质中聚腺苷酸（poly(A)+）RNA中的双链片段（c-ds）进行了研究。已证明长度约为40个碱基对的双链体具有分子间特征，并且源自单链RNA（ss-RNA）与含聚腺苷酸的RNA分子的互补区域之间的相互作用。较短的双链序列主要具有分子内性质。根据指纹分析数据，不同长度的双链序列在其寡核苷酸组成上也存在差异。在可的松的作用下，已证明在细胞质聚腺苷酸（poly(A)+）RNA群体中只有几种双链序列会增加。有人提出双链区域在基因表达的激素调节中的作用。
