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[大鼠肝脏含多聚腺苷酸的细胞质RNA中双链片段的研究]

[Study of the double-stranded fragments in the poly(A)-containing cytoplasmic RNA of the rat liver].

作者信息

Konstantinova I M, Petukhova O A, Kulichkova V A

出版信息

Mol Biol (Mosk). 1984 Jul-Aug;18(4):945-9.

PMID:6504031
Abstract

The double-stranded sequences in the poly(A)-containing cytoplasmic RNA (c-dsRNA) hybridize mainly with the repetitive DNA. 70-80% of double-stranded regions in the cytoplasmic poly (A)-RNA are identical to double-stranded regions of heterogeneous nuclear RNA in normal as well as in cortisone-treated rats. The thermal stability of cytoplasmic double-stranded regions is higher in the presence of polyadenylate sequences than in their absence. It is suggested that the double-stranded sequences in the poly (A) +RNA interact with poly (A) stretches and form higher order structures. The thermal stability of c-dsRNA isolated from cortisone-treated rats is higher than that from control rats.

摘要

含聚腺苷酸的细胞质RNA(c-dsRNA)中的双链序列主要与重复DNA杂交。在正常大鼠以及经可的松处理的大鼠中,细胞质聚腺苷酸RNA中70%-80%的双链区域与不均一核RNA的双链区域相同。在存在聚腺苷酸序列的情况下,细胞质双链区域的热稳定性高于不存在时。有人提出,聚腺苷酸RNA中的双链序列与聚腺苷酸片段相互作用并形成更高层次的结构。从经可的松处理的大鼠中分离出的c-dsRNA的热稳定性高于对照大鼠。

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1
[Study of the double-stranded fragments in the poly(A)-containing cytoplasmic RNA of the rat liver].[大鼠肝脏含多聚腺苷酸的细胞质RNA中双链片段的研究]
Mol Biol (Mosk). 1984 Jul-Aug;18(4):945-9.
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