Department of Geriatrics, University Medical Center Utrecht, Room B05.2.25, PO Box 85500, 3508, GA, Utrecht, Netherlands.
Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands.
Neuroradiology. 2021 Jul;63(7):1145-1148. doi: 10.1007/s00234-021-02680-4. Epub 2021 Mar 20.
Incidental basal ganglia calcifications are a common finding on computed tomography (CT). We investigated the histological characteristics of these calcifications and their association with CT findings, using post-mortem basal ganglia tissue from 22 patients. Eight patients had basal ganglia calcifications on histology, and six patients had calcifications on CT, varying from mild to severe. Four patients had calcifications identified by both histology and CT, and two patients had calcifications detected by CT but not by histology, possibly because of insufficient tissue available. Calcifications were found mainly in the tunica media of arterioles located in the globus pallidus, which suggests that incidental CT calcifications are vascular in nature. However, tunica media calcifications, and thereby incidental basal ganglia calcifications, are probably not related to atherosclerosis.
偶然发现的基底节钙化是计算机断层扫描（CT）的常见表现。我们使用 22 例尸检基底节组织研究了这些钙化的组织学特征及其与 CT 发现的关系。8 例患者的组织学上存在基底节钙化，6 例 CT 上存在钙化，从轻度到重度不等。4 例患者的组织学和 CT 均发现钙化，2 例患者 CT 发现钙化而组织学未发现，可能是因为组织量不足。钙化主要位于苍白球中小动脉的中膜，提示偶然 CT 钙化是血管性的。然而，中膜钙化，以及偶然的基底节钙化，可能与动脉粥样硬化无关。
