ICAR-IVRI, Hebbal, Bengaluru, 560024, India.
ICAR-NDRI-SRS, Adugoudi, Bengaluru, 560030, India.
Trop Anim Health Prod. 2021 Mar 20;53(2):217. doi: 10.1007/s11250-021-02653-y.
Biannual vaccination of the cattle with inactivated foot-and-mouth disease (FMD) vaccine is the control strategy in endemic countries. Reduction in the milk yield is one of the main reasons for poor compliance of the cattle owners to FMD vaccination. As it can adversely affect the herd immunity, the present study aimed to quantify the losses in the milk yield post-FMD vaccination. Retrospective data on the milk yield (kg) recordings, days in milk, parity, and age at vaccination of the Deoni and crossbred cows were collected from 10 days before (-10) to 10 days after (+10) FMD vaccination (dpv). Days in milk were categorized into three stages of lactation for Deoni and crossbred cows. Age (month) was categorized into four classes. Least squares means of the milk yield were generated after adjusting for year, age, parity, and stage of lactation. Based on exploratory data analysis, the corrected milk yield records from -2 to +2 dpv for 5 years comprising 614 data points on Deoni cows (n=54) and 488 data points on crossbred cows (n=55) were used for the final analysis. Because of the correlated errors on the corrected milk yield, linear mixed model ANOVA was done by fitting dpv as fixed effect and cow as random effect, and the results revealed the effect of dpv was non-significant (P>0.05) in either breed. With respect to dpv 0, a marginal reduction of 90 g in the corrected milk yield in the Deoni cow was recorded on dpv 1, while the reduction was about 360 g on dpv 0 as compared dpv -1 in the crossbred cow. It was concluded that FMD vaccination caused a transient non-significant reduction in the milk yield in the Deoni and crossbred cows.
在流行国家，对牛进行口蹄疫（FMD）灭活疫苗的双年度接种是控制策略。产奶量下降是牛主人不遵守 FMD 疫苗接种规定的主要原因之一。由于它会对群体免疫力产生不利影响，因此本研究旨在量化 FMD 疫苗接种后的产奶量损失。从 FMD 疫苗接种前 10 天（-10）到后 10 天（+10），收集了 Deoni 和杂交奶牛的产奶量（kg）记录、泌乳天数、胎次和接种年龄的回顾性数据。泌乳天数被分为 Deoni 和杂交奶牛的三个泌乳阶段。年龄（月）分为四个等级。调整年份、年龄、胎次和泌乳阶段后，生成产奶量的最小二乘均值。基于探索性数据分析，使用 5 年来从-2 到+2 dpv 的校正产奶量记录，包括 Deoni 牛（n=54）的 614 个数据点和杂交奶牛（n=55）的 488 个数据点，用于最终分析。由于校正产奶量的相关误差，通过拟合 dpv 作为固定效应和牛作为随机效应进行线性混合模型方差分析，结果表明 dpv 对两种品种的影响均不显著（P>0.05）。关于 dpv 0，在 Deoni 牛中，在 dpv 1 时记录到校正产奶量减少了 90g，而在杂交奶牛中，与 dpv -1 相比，在 dpv 0 时减少了约 360g。研究结论认为，FMD 疫苗接种会导致 Deoni 和杂交奶牛的产奶量短暂且无显著减少。
