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影响额窦切开术通畅结局的预后变量及处理方法:一项前瞻性研究。

The prognostic variables affecting the frontal sinusotomy patency outcome and how to manage: A prospective study.

机构信息

Department of Otorhinolaryngology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Department of Otorhinolaryngology, Faculty of Medicine, Kafrelsheikh University, Kafr el-Sheikh, Egypt.

出版信息

Clin Otolaryngol. 2021 Sep;46(5):969-975. doi: 10.1111/coa.13761. Epub 2021 Apr 5.

Abstract

OBJECTIVES

The study aimed to assess the factors affecting the frontal sinus patency after endoscopic frontal sinusotomy.

DESIGN

A prospective cohort study.

SETTING

Tertiary centre hospital.

MAIN OUTCOME MEASURES

Fifty patients with refractory chronic frontal sinusitis (83 operated frontal sinuses) had frontal sinusotomy and followed up for six months. Multiple operative factors were included the type of the procedure, intraoperative sinus findings, degree of mucosal preservation and middle turbinate stability. Other factors were also assessed, including smoking, the presence of allergic rhinitis, asthma, gastroesophageal reflux and other associated medical comorbidities.

RESULTS

The sinus patency success rate was 75.9%. There was a significant difference regarding the intraoperative anteroposterior sinus ostium diameter (5.36 ± 1.45 mm vs 8.88 ± 2.38 mm, P-value: .001* in the failed group and the success group, respectively). There was a significant association between the patency outcome and the presence of associated medical comorbidities (P-value: .001*), the presence of allergic rhinitis (P-value: .001*), the degree of sinus mucosal preservation (P-value: .012*) and the degree of middle turbinate stability (P-value: .001*). The multivariate analysis showed that the intraoperative anteroposterior diameter of the sinus ostium, middle turbinate stability and presence of allergic rhinitis were significant predictors (P-value: .012*, .042* and .013*, respectively).

CONCLUSION

Sinuses with anteroposterior ostium diameters less than 5.36 mm are more susceptible to restenosis. The flail middle turbinate increases the risk of postoperative middle meatus synechia and frontal sinus patency failure. The presence of allergic rhinitis has a negative impact on the patency outcome.

摘要

目的

本研究旨在评估内镜额窦切开术后额窦通畅的影响因素。

设计

前瞻性队列研究。

地点

三级中心医院。

主要观察指标

50 例难治性慢性额窦炎患者(83 例手术额窦)行额窦切开术,随访 6 个月。包括手术类型、术中窦腔发现、黏膜保留程度和中鼻甲稳定性在内的多种手术因素。还评估了吸烟、变应性鼻炎、哮喘、胃食管反流病和其他相关合并症的存在等其他因素。

结果

窦腔通畅成功率为 75.9%。术中前后窦口直径(分别为 5.36±1.45mm 和 8.88±2.38mm)在失败组和成功组之间存在显著差异(P 值:.001*)。通畅结果与合并症的存在(P 值:.001*)、变应性鼻炎的存在(P 值:.001*)、窦黏膜保留程度(P 值:.012*)和中鼻甲稳定性(P 值:.001*)有显著相关性。多变量分析显示,术中前后窦口直径、中鼻甲稳定性和变应性鼻炎是显著的预测因素(P 值:.012*、.042和.013)。

结论

前后径小于 5.36mm 的窦腔更容易再狭窄。活动中鼻甲增加了术后中鼻道粘连和额窦通畅失败的风险。变应性鼻炎的存在对通畅结果有负面影响。

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