North Carolina State University, Department of Biological Sciences, Meitzen Laboratory, Campus Box 7617, 128 David Clark Labs, Raleigh, NC 27695-7617, USA.
Biosystems. 2021 Jul;205:104403. doi: 10.1016/j.biosystems.2021.104403. Epub 2021 Mar 18.
What is the form of dynamic, e.g., sensory, information in the mammalian cortex? Information in the cortex is modeled as a coherence map of a mixed chimera state of synchronous, phasic, and disordered minicolumns. The theoretical model is built on neurophysiological evidence. Complex spatiotemporal information is instantiated through a system of interacting biological processes that generate a synchronized cortical area, a coherent aperture. Minicolumn elements are grouped in macrocolumns in an array analogous to a phased-array radar, modeled as an aperture, a "hole through which radiant energy flows." Coherence maps in a cortical area transform inputs from multiple sources into outputs to multiple targets, while reducing complexity and entropy. Coherent apertures can assume extremely large numbers of different information states as coherence maps, which can be communicated among apertures with corresponding very large bandwidths. The coherent aperture model incorporates considerable reported research, integrating five conceptually and mathematically independent processes: 1) a damped Kuramoto network model, 2) a pumped area field potential, 3) the gating of nearly coincident spikes, 4) the coherence of activity across cortical lamina, and 5) complex information formed through functions in macrocolumns. Biological processes and their interactions are described in equations and a functional circuit such that the mathematical pieces can be assembled the same way the neurophysiological ones are. The model can be conceptually convolved over the specifics of local cortical areas within and across species. A coherent aperture becomes a node in a graph of cortical areas with a corresponding distribution of information.
哺乳动物皮层中的动态信息（例如感觉信息）是什么形式的？皮层中的信息被建模为同步、相位和无序的微柱列混合嵌合体状态的相干图。该理论模型建立在神经生理学证据的基础上。复杂的时空信息是通过一系列相互作用的生物过程来实现的，这些过程产生了一个同步的皮层区域，即一个相干孔径。微柱列元素以类似于相控阵雷达的方式分组在宏柱列中，被建模为孔径，即“辐射能流动的孔”。皮层区域中的相干图将来自多个源的输入转换为到多个目标的输出，同时降低复杂性和熵。相干孔径可以作为相干图呈现出极其大量的不同信息状态，这些状态可以通过相应的非常大的带宽在孔径之间进行通信。相干孔径模型包含了大量已报道的研究，整合了五个概念上和数学上独立的过程：1）阻尼 Kuramoto 网络模型，2）泵送区域场电位，3）几乎同时发生的尖峰的门控，4）皮质层之间的活动相干性，5）通过宏柱列中的函数形成的复杂信息。生物过程及其相互作用以方程和功能电路的形式描述，使得数学部分可以以与神经生理学部分相同的方式组装。该模型可以在物种内和物种间的局部皮质区域的具体细节上进行概念上的卷积。相干孔径成为具有相应信息分布的皮质区域图中的一个节点。
