Nissilä M, Isomäki H, Koota K, Larsen A, Raunio K
Scand J Rheumatol. 1977;6(3):158-60. doi: 10.3109/03009747709095442.
Ninety-nine adult RA patients with knee joint synovitis were randomized into two groups. The knee joints of the first group (52 patients) were treated with osmic acid and those of the second group (47 patients) with a placebo. After 6 months, the incidence of hydrops and pain was statistically less significant in joints treated with osmic acid. the result was better in joints without advanced radiological destruction. It is concluded that osmic acid is still of benefit in the local treatment of rheumatoid knee joint synovitis at an early stage.
99例患有膝关节滑膜炎的成年类风湿关节炎患者被随机分为两组。第一组（52例患者）的膝关节用锇酸治疗，第二组（47例患者）用安慰剂治疗。6个月后，用锇酸治疗的关节中积液和疼痛的发生率在统计学上显著降低。在没有严重放射学破坏的关节中结果更好。结论是锇酸在类风湿膝关节滑膜炎的早期局部治疗中仍然有益。
