革兰氏阴性菌的外膜囊泡：生物发生概述
Outer Membrane Vesicles of Gram-Negative Bacteria: An Outlook on Biogenesis.
作者信息
Avila-Calderón Eric Daniel, Ruiz-Palma María Del Socorro, Aguilera-Arreola Ma Guadalupe, Velázquez-Guadarrama Norma, Ruiz Enrico A, Gomez-Lunar Zulema, Witonsky Sharon, Contreras-Rodríguez Araceli
机构信息
Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, México City, Mexico.
Departamento de Biología Celular, Centro de Investigación y de Estudios Avanzados, Instituto Politécnico Nacional, CINVESTAV-IPN, México City, Mexico.
出版信息
Front Microbiol. 2021 Mar 4;12:557902. doi: 10.3389/fmicb.2021.557902. eCollection 2021.
Outer membrane vesicles (OMVs) from Gram-negative bacteria were first described more than 50 years ago. However, the molecular mechanisms involved in biogenesis began to be studied only in the last few decades. Presently, the biogenesis and molecular mechanisms for their release are not completely known. This review covers the most recent information on cellular components involved in OMV biogenesis, such as lipoproteins and outer membrane proteins, lipopolysaccharide, phospholipids, quorum-sensing molecules, and flagella.
革兰氏阴性菌的外膜囊泡（OMV）早在50多年前就被首次描述。然而，其生物发生所涉及的分子机制直到最近几十年才开始被研究。目前，其生物发生及释放的分子机制尚未完全明确。这篇综述涵盖了关于参与OMV生物发生的细胞成分的最新信息，如脂蛋白和外膜蛋白、脂多糖、磷脂、群体感应分子和鞭毛。
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