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左西孟旦在各种病因所致急性心力衰竭患者的现代治疗中的应用。

Levosimendan in the modern treatment of patients with acute heart failure of various aetiologies.

作者信息

Glinka Lidia, Mayzner-Zawadzka Ewa, Onichimowski Dariusz, Jalali Rakesh, Glinka Maciej

机构信息

2 Anaesthesiology and Intensive Care Clinical Ward, Clinical University Hospital, Department of Anaesthesiology and Intensive Care, University of Warmia and Mazury, Olsztyn, Poland.

1 Clinical Department of Anaesthesiology and Intensive Care, Regional Specialist Hospital, Olsztyn, Poland.

出版信息

Arch Med Sci. 2019 Nov 7;17(2):296-303. doi: 10.5114/aoms.2018.77055. eCollection 2021.

Abstract

Acute decompensated heart failure (ADHF) is a common clinical problem associated with a high mortality rate. Because ADHF has various aetiologies, there are a range of therapeutic options, among others, positive inotropes (inotropic drugs). As an inotropic agent whose mechanism is different than that of "classical" medicines, levosimendan (LSM) is one of the most common therapeutic options. Despite many publications on LSM, some issues related to its application remain unclear. The authors of this paper have attempted to summarise expert recommendations and reports available in the literature.

摘要

急性失代偿性心力衰竭(ADHF)是一个常见的临床问题,死亡率很高。由于ADHF有多种病因,因此有一系列治疗选择,其中包括正性肌力药(强心药)。左西孟旦(LSM)作为一种作用机制与“传统”药物不同的强心剂,是最常用的治疗选择之一。尽管有许多关于LSM的出版物,但其应用的一些问题仍不明确。本文作者试图总结文献中可用的专家建议和报告。

相似文献

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Levosimendan: beyond its simple inotropic effect in heart failure.左西孟旦:超越其在心力衰竭中单纯的正性肌力作用。
Pharmacol Ther. 2007 May;114(2):184-97. doi: 10.1016/j.pharmthera.2007.01.008. Epub 2007 Feb 16.
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Advances in chemical pharmacotherapy for managing acute decompensated heart failure.急性失代偿性心力衰竭化学药物治疗的进展
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本文引用的文献

1
Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis.左西孟旦用于预防脓毒症急性器官功能障碍
N Engl J Med. 2016 Oct 27;375(17):1638-1648. doi: 10.1056/NEJMoa1609409. Epub 2016 Oct 5.
3
Role of levosimendan in the management of subarachnoid hemorrhage.左西孟旦在蛛网膜下腔出血治疗中的作用。
Am J Emerg Med. 2016 Feb;34(2):298-306. doi: 10.1016/j.ajem.2015.11.024. Epub 2015 Nov 25.

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