Glinka Lidia, Mayzner-Zawadzka Ewa, Onichimowski Dariusz, Jalali Rakesh, Glinka Maciej
2 Anaesthesiology and Intensive Care Clinical Ward, Clinical University Hospital, Department of Anaesthesiology and Intensive Care, University of Warmia and Mazury, Olsztyn, Poland.
1 Clinical Department of Anaesthesiology and Intensive Care, Regional Specialist Hospital, Olsztyn, Poland.
Arch Med Sci. 2019 Nov 7;17(2):296-303. doi: 10.5114/aoms.2018.77055. eCollection 2021.
Acute decompensated heart failure (ADHF) is a common clinical problem associated with a high mortality rate. Because ADHF has various aetiologies, there are a range of therapeutic options, among others, positive inotropes (inotropic drugs). As an inotropic agent whose mechanism is different than that of "classical" medicines, levosimendan (LSM) is one of the most common therapeutic options. Despite many publications on LSM, some issues related to its application remain unclear. The authors of this paper have attempted to summarise expert recommendations and reports available in the literature.
急性失代偿性心力衰竭(ADHF)是一个常见的临床问题,死亡率很高。由于ADHF有多种病因,因此有一系列治疗选择,其中包括正性肌力药(强心药)。左西孟旦(LSM)作为一种作用机制与“传统”药物不同的强心剂,是最常用的治疗选择之一。尽管有许多关于LSM的出版物,但其应用的一些问题仍不明确。本文作者试图总结文献中可用的专家建议和报告。