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我如何治疗发热性中性粒细胞减少症。

How I Treat Febrile Neutropenia.

作者信息

Nucci Marcio

机构信息

Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

出版信息

Mediterr J Hematol Infect Dis. 2021 Mar 1;13(1):e2021025. doi: 10.4084/MJHID.2021.025. eCollection 2021.

DOI:10.4084/MJHID.2021.025
PMID:33747406
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7938921/
Abstract

The management of febrile neutropenia is a backbone of treating patients with hematologic malignancies and has evolved over the past decades. This article reviews my approach to the evaluation and treatment of febrile neutropenic patients. Key topics discussed include antibacterial and antifungal prophylaxis, the initial workup for fever, the choice of the empiric antibiotic regimen and its modifications, and criteria for discontinuation. For each of these questions, I review the literature and present my perspective.

摘要

发热性中性粒细胞减少症的管理是治疗血液系统恶性肿瘤患者的核心内容,在过去几十年中不断发展。本文回顾了我对发热性中性粒细胞减少症患者的评估和治疗方法。讨论的关键主题包括抗菌和抗真菌预防、发热的初始检查、经验性抗生素方案的选择及其调整,以及停药标准。对于这些问题中的每一个,我都回顾了相关文献并阐述了我的观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2e/7938921/1b5000d51523/mjhid-13-1-e2021025f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2e/7938921/1b5000d51523/mjhid-13-1-e2021025f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2e/7938921/1b5000d51523/mjhid-13-1-e2021025f1.jpg

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How I Treat Febrile Neutropenia.我如何治疗发热性中性粒细胞减少症。
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Infect Control Hosp Epidemiol. 2021 Jul;42(7):853-856. doi: 10.1017/ice.2020.1299. Epub 2020 Nov 24.
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Early discontinuation of empirical antibiotic treatment in neutropenic patients with acute myeloid leukaemia and high-risk myelodysplastic syndrome.中性粒细胞减少的急性髓系白血病和高危骨髓增生异常综合征患者经验性抗生素治疗的早期停药。
Antimicrob Resist Infect Control. 2020 May 27;9(1):74. doi: 10.1186/s13756-020-00729-2.
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Open Forum Infect Dis. 2024 Feb 1;11(3):ofae052. doi: 10.1093/ofid/ofae052. eCollection 2024 Mar.
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