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A commonly occurring genetic variant within the NPLOC4-TSPAN10-PDE6G gene cluster is associated with the risk of strabismus.NPLOC4-TSPAN10-PDE6G 基因簇内常见的遗传变异与斜视风险相关。
Hum Genet. 2019 Jul;138(7):723-737. doi: 10.1007/s00439-019-02022-8. Epub 2019 May 9.
2
Surgical management of intermittent exotropia: do we have an answer for all?间歇性外斜视的手术治疗:我们能给出适用于所有情况的答案吗?
BMJ Open Ophthalmol. 2019 Mar 8;4(1):e000243. doi: 10.1136/bmjophth-2018-000243. eCollection 2019.
3
[Evalution of life quality of children with intermittent exotropia one year after the effective surgical treatment].[间歇性外斜视有效手术治疗一年后儿童生活质量的评估]
Zhonghua Yan Ke Za Zhi. 2019 Jan 11;55(1):31-36. doi: 10.3760/cma.j.issn.0412-4081.2019.01.007.
4
The Development of the Chinese Intermittent Exotropia Questionnaire.《中国间歇性外斜视问卷》的研制
Optom Vis Sci. 2017 Jun;94(6):707-713. doi: 10.1097/OPX.0000000000001080.
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What's new for us in strabismus?斜视领域对我们来说有哪些新进展?
Indian J Ophthalmol. 2017 Mar;65(3):184-190. doi: 10.4103/ijo.IJO_867_16.
6
[Utilization of Quality-of-life assessment Questionnaires for Intermittent Exotropia in China].[中国间歇性外斜视生活质量评估问卷的应用]
Zhonghua Yan Ke Za Zhi. 2016 Aug;52(8):596-603. doi: 10.3760/cma.j.issn.0412-4081.2016.08.008.
7
The Impact of Congenital Strabismus Surgery on Quality of Life in Children.先天性斜视手术对儿童生活质量的影响。
J Ophthalmic Vis Res. 2016 Apr-Jun;11(2):188-92. doi: 10.4103/2008-322X.183918.
8
Quality of Life and Strabismus Surgery in Children.儿童生活质量与斜视手术
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Impact of strabismus on the quality of life of Chinese Han teenagers.斜视对中国汉族青少年生活质量的影响。
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Management of Strabismus in Myopes.近视患者斜视的管理
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成人间歇性外斜视的生活质量及危险因素

Quality of life in adult intermittent exotropia and the risk factors.

作者信息

Zhao Bo-Wen, Fu Jing, Wang Jing-Hui, Bai Hai-Xia, Liu Pei-Pei, Guo Ya-Nan, Zhang Rong-Han, Su Han

机构信息

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing 100730, China.

Eye Center, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.

出版信息

Int J Ophthalmol. 2021 Mar 18;14(3):442-447. doi: 10.18240/ijo.2021.03.18. eCollection 2021.

DOI:10.18240/ijo.2021.03.18
PMID:33747823
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7930552/
Abstract

AIM

To study the quality of life of adult patients with intermittent exotropia (IXT) in China and analyze the factors affecting the quality of life in IXT patients.

METHODS

Totally 109 cases of normal eye (control group), 77 cases of IXT (IXT group) and 115 cases of strabismus control group (except IXT) were collected. The quality of life of the patients was assessed by Chinese version of adult strabismus patient's quality of life scale (CAS-20). The differences of general characteristics, visual function and quality of life were analyzed, and the effects of individual factors and visual function on quality of life of patients with IXT were analyzed.

RESULTS

The IXT group had a high proportion of patients with family history, low proportion of patients with amblyopia compared with strabismus control group. The proportion with normal near and far stereopsis of IXT group were lower than that of normal control group. The best corrected visual acuity of IXT group was higher than that of strabismus control group, but lower than the control group. In addition, the median strabismus degree in IXT group was higher than that in other strabismus control group. The median psychosocial scores and median visual function scores of the IXT group was lower than that of the normal control group, but not different from strabismus control group. Occupation status, course of disease, far stereopsis and near stereopsis significantly affected the quality of life in IXT patients.

CONCLUSION

Adult IXT patients in China have a certain proportion of family history and lower quality of life, The main factors affecting the quality of life of IXT patients is stereopsis, course of disease and occupation status.

摘要

目的

研究中国成年间歇性外斜视(IXT)患者的生活质量,并分析影响IXT患者生活质量的因素。

方法

共收集109例正常眼患者(对照组)、77例IXT患者(IXT组)和115例斜视对照组患者(不包括IXT)。采用中文版成人斜视患者生活质量量表(CAS-20)评估患者的生活质量。分析一般特征、视功能和生活质量的差异,并分析个体因素和视功能对IXT患者生活质量的影响。

结果

与斜视对照组相比,IXT组有家族史的患者比例较高,弱视患者比例较低。IXT组近、远立体视正常的比例低于正常对照组。IXT组的最佳矫正视力高于斜视对照组,但低于对照组。此外,IXT组的斜视度中位数高于其他斜视对照组。IXT组的心理社会得分中位数和视功能得分中位数低于正常对照组,但与斜视对照组无差异。职业状态、病程、远立体视和近立体视显著影响IXT患者的生活质量。

结论

中国成年IXT患者有一定比例的家族史且生活质量较低,影响IXT患者生活质量的主要因素是立体视、病程和职业状态。