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台湾医师的癌症风险:一项基于人群的倾向评分匹配队列研究

The Cancer Risk among Physicians in Taiwan, a Population-Based Propensity Score Matched Cohort Study.

作者信息

Yang Hsin-Yi, Chen Cheng-Ren, Lee Shih-Yu, Tsai Wen-Chen, Hsu Yueh-Han

机构信息

Department of Medical Research, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chia-Yi City, Taiwan.

Department of Internal Medicine, Ditmansion Medical Foundation Chia-Yi Christian Hospital, Chia-Yi City, Taiwan.

出版信息

Iran J Public Health. 2021 Feb;50(2):297-305. doi: 10.18502/ijph.v50i2.5344.

DOI:10.18502/ijph.v50i2.5344
PMID:33747993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7956082/
Abstract

BACKGROUND

The field of physician health is gaining increasing attention; however, most research and interventions have concentrated on factors such as job stress, mental health, and substance abuse. The risks of major cancers in physicians remain unclear. We used a propensity score-matched analysis to investigate the risk of cancer in physicians relative to the general population who had no healthcare-related professional background.

METHODS

Data were obtained from the National Health Insurance system in Taiwan. The physician cohort contained 29,713 physicians, and each physician was propensity score-matched with a person from the general population.

RESULTS

The physicians demonstrated a 0.90-fold lower risk of all-cancers (95% confidence interval [CI] = 0.83 - 0.96) when compared with the general population. Female physicians had a higher risk of cancer than male physicians (adjusted hazard ratio [HR] = 1.59; 95% CI = 1.28 - 1.96). Physicians had higher risks of prostate (HR = 1.26; 95% CI = 1.00 - 1.59) and thyroid cancers (HR = 3.16; 95% CI = 1.69 - 5.90) when compared with the general population.

CONCLUSION

Physicians have lower rates of overall cancer risk than the general population. Female physicians have higher cancer risks than male physicians. Male physicians have higher risks of thyroid and prostate cancer relative to the general population.

摘要

背景

医师健康领域正日益受到关注;然而,大多数研究和干预措施都集中在工作压力、心理健康和药物滥用等因素上。医师患主要癌症的风险仍不明确。我们采用倾向评分匹配分析来研究医师相对于没有医疗保健相关专业背景的普通人群患癌症的风险。

方法

数据来自台湾国民健康保险系统。医师队列包含29713名医师,每位医师都与一名普通人群进行倾向评分匹配。

结果

与普通人群相比,医师患所有癌症的风险降低了0.90倍(95%置信区间[CI]=0.83-0.96)。女医师患癌症的风险高于男医师(调整后风险比[HR]=1.59;95%CI=1.28-1.96)。与普通人群相比,医师患前列腺癌(HR=1.26;95%CI=1.00-1.59)和甲状腺癌(HR=3.16;95%CI=1.69-5.90)的风险更高。

结论

医师总体患癌风险率低于普通人群。女医师患癌风险高于男医师。相对于普通人群,男医师患甲状腺癌和前列腺癌的风险更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449f/7956082/ae07647a45bb/IJPH-50-297-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449f/7956082/ae07647a45bb/IJPH-50-297-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449f/7956082/ae07647a45bb/IJPH-50-297-g001.jpg

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Cancer Incidence in Physicians: A Taiwan National Population-based Cohort Study.医师中的癌症发病率:一项基于台湾全国人口的队列研究。
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