Street E W
Scott Med J. 1977 Oct;22(4):279-85. doi: 10.1177/003693307702200409.
The story is told of how streptomycin, PAS and isoniazid came to be known as the first-line drugs. Although the present first line is generally accepted as rifampicin, ethambutol and isoniazid, the way in which these drugs should be used in different types of tuberculosis and in different parts of the world is discussed in relation to efficacy, toxicity and cost. Passing reference is also made to second-line drugs used in the retreatment of cases with bacterial resistance.
关于链霉素、对氨基水杨酸和异烟肼如何成为一线药物的故事如下。尽管目前普遍认为一线药物是利福平、乙胺丁醇和异烟肼，但本文将从疗效、毒性和成本方面讨论这些药物在不同类型结核病以及世界不同地区的使用方式。文中还顺便提及了用于治疗细菌耐药病例的二线药物。
