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短期口服阿苯达唑治疗弥漫性单侧亚急性神经视网膜炎:一例报告。

Short-term oral albendazole therapy for diffuse unilateral subacute neuroretinitis: A case report.

作者信息

Amaral Claudia, Jimenez Hiram, Davila Pedro, Ulloa-Padilla Jan P, Guiot Humberto M, Oliver Armando L

机构信息

University of Puerto Rico, Medical Sciences Campus, School of Medicine, San Juan, PR, USA.

University of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, San Juan, PR, USA.

出版信息

Am J Ophthalmol Case Rep. 2021 Mar 6;22:101054. doi: 10.1016/j.ajoc.2021.101054. eCollection 2021 Jun.

DOI:10.1016/j.ajoc.2021.101054
PMID:33748536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7970060/
Abstract

PURPOSE

To report on a case of diffuse unilateral subacute neuroretinitis (DUSN) that was successfully treated with a short course of oral albendazole.

OBSERVATIONS

A 51-year-old male presented with severe visual loss secondary to DUSN associated with a positive serology. Because the parasite could not be detected on fundoscopy, first-line treatment with photocoagulation could not be administered. Treatment with a 6-day course of oral albendazole resulted in the resolution of DUSN as well as the restoration of visual acuity.

CONCLUSION AND IMPORTANCE

Although DUSN is characterized by the presence of a parasitic organism in the retina, there are cases in which the parasite is not visible. Albendazole has been used to treat such cases, but a standard treatment regimen has not been determined yet. Our case suggests that the resolution of DUSN can be achieved with short-term albendazole therapy.

摘要

目的

报告一例经短期口服阿苯达唑成功治疗的弥漫性单侧亚急性神经视网膜炎(DUSN)病例。

观察结果

一名51岁男性因DUSN继发严重视力丧失,血清学检查呈阳性。由于在眼底镜检查中未检测到寄生虫,无法进行光凝一线治疗。口服阿苯达唑6天疗程的治疗使DUSN得到缓解,视力也得以恢复。

结论与意义

尽管DUSN的特征是视网膜中存在寄生虫,但在某些情况下寄生虫不可见。阿苯达唑已用于治疗此类病例,但尚未确定标准治疗方案。我们的病例表明,短期阿苯达唑治疗可使DUSN得到缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12de/7970060/bbb932945a99/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12de/7970060/3a6e4e6cc704/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12de/7970060/bbb932945a99/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12de/7970060/3a6e4e6cc704/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12de/7970060/bbb932945a99/gr2.jpg

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本文引用的文献

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J Ophthalmic Inflamm Infect. 2019 Dec 27;9(1):23. doi: 10.1186/s12348-019-0191-x.
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Ocular manifestations of bartonellosis.巴尔通体病的眼部表现。
Curr Opin Ophthalmol. 2018 Nov;29(6):582-587. doi: 10.1097/ICU.0000000000000522.
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Recent Developments in the Diagnosis and Treatment of Ocular Toxoplasmosis.眼部弓形虫病诊断与治疗的最新进展
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Clinical experience in treatment of diffuse unilateral subretinal neuroretinitis.弥漫性单侧视网膜下神经视网膜炎的治疗临床经验
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Diffuse unilateral subacute neuroretinitis in a young boy: a case report.一名年轻男孩的弥漫性单侧亚急性神经视网膜炎:病例报告
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"Worm in the eye": the rationale for treatment of DUSN in south India.“眼中之虫”:印度南部盘尾丝虫性弥漫性单侧亚急性神经视网膜炎的治疗原理
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