儿童早发性炎症性肠病相关肠病性关节炎皮肤综合征。
Bowel-associated dermatosis-arthritis syndrome in a child with very early onset inflammatory bowel disease.
机构信息
Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
出版信息
Pediatr Dermatol. 2021 May;38(3):697-698. doi: 10.1111/pde.14544. Epub 2021 Mar 21.
A 6-year-old boy with severe very early-onset inflammatory bowel disease (VEO-IBD) was admitted for 1 week of high fevers, loose stools, joint pains, and myalgias. He subsequently developed a progressive, papular, and vesiculopustular eruption on his face with rapid spread to his trunk and extremities. Histopathology demonstrated dense dermal neutrophilic inflammation. Findings were consistent with bowel-associated dermatosis-arthritis syndrome (BADAS), which is rarely reported in children and requires further characterization.
一名 6 岁男孩患有严重的早发性炎症性肠病（VEO-IBD），因高热、腹泻、关节痛和肌痛入院 1 周。随后，他的面部出现进行性丘疹、水疱和脓疱疹，并迅速扩散至躯干和四肢。组织病理学显示致密的真皮中性粒细胞炎症。这些发现符合肠相关性皮肤病关节炎综合征（BADAS），该疾病在儿童中很少见，需要进一步明确。
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