College of Pharmacy, QU Health, Qatar University, Doha, 2713, Qatar.
School of Polymer Science and Engineering, University of Southern Mississippi, Hattiesburg, Mississippi, 39406, USA.
J Biomed Mater Res B Appl Biomater. 2021 Nov;109(11):1893-1908. doi: 10.1002/jbm.b.34828. Epub 2021 Mar 21.
Since the discovery and fabrication of carbon nanofibers (CNFs) over a decade ago, scientists foster to discover novel myriad potential applications for this material in both biomedicine and industry. The unique economic viability, mechanical, electrical, optical, thermal, and structural properties of CNFs led to their rapid emergence. CNFs become an artificial intelligence platform for different uses, including a wide range of biomedical applications. Furthermore, CNFs have exceptionally large surface areas that make them flexible for tailoring and functionalization on demand. This review highlights the recent progress and achievements of CNFs in a wide range of biomedical fields, including cancer therapy, biosensing, tissue engineering, and wound dressing. Besides the synthetic techniques of CNFs, their potential toxicity and limitations, as biomaterials in real clinical settings, will be presented. This review discusses CNF's future investigations in other biomedical fields, including gene delivery and bioimaging and CNFs risk assessment.
自十多年前发现和制造碳纳米纤维（CNF）以来，科学家们一直致力于发现这种材料在生物医学和工业领域的新的、多种多样的潜在应用。CNF 具有独特的经济可行性、机械、电气、光学、热学和结构特性，这使得它们迅速崛起。CNF 成为不同用途的人工智能平台，包括广泛的生物医学应用。此外，CNF 具有非常大的表面积，使其能够灵活地按需进行定制和功能化。这篇综述重点介绍了 CNF 在癌症治疗、生物传感、组织工程和伤口敷料等广泛的生物医学领域的最新进展和成就。除了 CNF 的合成技术外，还将介绍其作为生物材料在实际临床环境中的潜在毒性和局限性。本综述讨论了 CNF 在其他生物医学领域的未来研究，包括基因传递和生物成像以及 CNF 风险评估。
