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[颞骨放线菌病。一例儿科病例报告]

[Actinomycosis in temporal bone. A pediatric case report].

作者信息

Fernández Lucía V, Arias Elena, Cohen Daniela, Spini Roxana

机构信息

Residencia de Otorrinolaringología Infantil, Hospital General de Niños Pedro de Elizalde, Ciudad Autónoma de Buenos Aires, Argentina.

División de Otorrinolaringología, Hospital General de Niños Pedro de Elizalde, Ciudad Autónoma de Buenos Aires, Argentina.

出版信息

Arch Argent Pediatr. 2021 Apr;119(2):e153-e157. doi: 10.5546/aap.2021.e153.

Abstract

Actinomycosis is an infection caused by a Gram-positive, filamentous anaerobic bacillus. Mainly belonging to the human commensal flora of the oropharynx, it normally colonizes the human digestive and genital tracts and the bronchial tree. It is slightly frequent in the temporal bone. Bacterial cultures and pathology are the cornerstone of diagnosis, but particular conditions are required in order to get the correct diagnosis. Prolonged bacterial cultures in anaerobic conditions are necessary to identify the bacterium and typical microscopic findings include necrosis with yellowish sulfur granules and filamentous Gram-positive fungal-like pathogens. Patients with actinomycosis require prolonged (6- to 12-month) high doses of penicillin G or amoxicillin, but the duration of antimicrobial therapy could probably be shortened in patients in whom optimal surgical resection of infected tissues has been performed. A pediatric patient with actinomycosis in temporal bone who needed surgery resolution is reported.

摘要

放线菌病是由革兰氏阳性丝状厌氧杆菌引起的一种感染。它主要属于口咽部位的人体共生菌群,通常定植于人体消化道、生殖道和支气管树。在颞骨中较为常见。细菌培养和病理学检查是诊断的基石,但为了做出正确诊断需要特定条件。在厌氧条件下进行长时间的细菌培养对于鉴定该细菌是必要的,典型的显微镜检查结果包括伴有淡黄色硫磺颗粒的坏死以及丝状革兰氏阳性真菌样病原体。放线菌病患者需要长时间(6至12个月)大剂量使用青霉素G或阿莫西林,但对于已对感染组织进行最佳手术切除的患者,抗菌治疗的持续时间可能会缩短。本文报道了一名颞骨放线菌病的儿科患者,其需要通过手术解决问题。

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