Quintessence Int. 2021 Jun 9;52(7):596-605. doi: 10.3290/j.qi.b1098303.
Bleaching sensitivity (BS) is the most common adverse effect of tooth bleaching treatments. This study evaluated the effect of adding 1% sodium hexametaphosphate (SHMP) on BS and the whitening effectiveness of a bleaching gel.
Two maxillary quadrants from 26 patients were randomly assigned to the experimental and control groups in a split-mouth design. In the control group the at-home bleaching gel containing 3% hydrogen peroxide, and in the experimental quadrant the same gel with 1% SHMP, were applied in individual trays for 6 hours per night for 2 weeks. The patients' sensitivity to cold and touch as well as spontaneous sensitivity were recorded based on a visual analog scale (VAS). Changes in shade guide units (ΔSGU) and ΔE were measured using a spectrophotometer. Data were analyzed using the Kolmogorov-Smirnov, Mann-Whitney U, Wilcoxon signed-rank test, and independent sample t test.
Twenty-four patients completed the study. After 2 weeks, the sensitivity to cold and touch was significantly lower in the intervention group compared to the control (P = .015 and P = .039, respectively). The spontaneous sensitivity revealed no significant alteration between these two groups and during the bleaching period in each group (P > .050). Regarding both color measurements, the bleaching effectiveness in both groups was comparable, with no noticeable difference (P > .050).
The application of 1% SHMP was able to reduce the BS with no detrimental effect on the at-home bleaching effectiveness. (Quintessence Int 2021;52:596-605; doi: 10.3290/j.qi.b1098303).
漂白敏感性（BS）是牙齿漂白治疗最常见的不良反应。本研究评估了添加 1%六偏磷酸钠（SHMP）对 BS 和漂白凝胶美白效果的影响。
将 26 名患者的两个上颌象限随机分配到实验组和对照组的分割口腔设计中。在对照组中，使用含有 3%过氧化氢的家庭用漂白凝胶，而在实验组中，使用含有 1% SHMP 的相同凝胶，在单独的托盘上每天晚上应用 6 小时，持续 2 周。根据视觉模拟量表（VAS）记录患者对冷和触诊的敏感性以及自发性敏感性。使用分光光度计测量比色导板单位（ΔSGU）和ΔE 的变化。使用 Kolmogorov-Smirnov、Mann-Whitney U、Wilcoxon 符号秩检验和独立样本 t 检验分析数据。
24 名患者完成了研究。2 周后，干预组对冷和触诊的敏感性明显低于对照组（P =.015 和 P =.039）。两组之间以及每组在漂白期间的自发性敏感性均无明显变化（P >.050）。对于两种颜色测量，两组的漂白效果相当，无明显差异（P >.050）。
应用 1% SHMP 能够降低 BS，而对家庭用漂白效果无不利影响。（《国际口腔医学杂志》2021；52：596-605；doi：10.3290/j.qi.b1098303）
