Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials, School of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, Mongolia.
Key Laboratory of Medicinal and Edible Plants Resources of Hainan Province, Hainan Vocational University of Science and Technology, Haikou 571126, China.
Inorg Chem. 2021 Apr 5;60(7):5282-5289. doi: 10.1021/acs.inorgchem.1c00263. Epub 2021 Mar 22.
Fluoroquinolone antibiotic (FQ) residues, such as ciprofloxacin (CIP) and ofloxacin (OFLX), have aroused public concerns owing to their serious impact in environmental water or food fields which influence human health. A facile and high-performance sensory method for detecting FQs is highly desirable for practical requirements. Herein, we have presented a luminescent Eu-MOF with unique 2D (4-c) {4.6}-connected topology, which holds the outstanding fluorescent property and excellent chemical stability in aqueous solution for 15 days. Thus, Eu-MOF can be considered as a highly sensitive chemo-sensor for sensing CIP and OFLX with different fluorescent color conversion (red changes to green for OFLX and to blue for CIP) and a low detection limit of 0.693 and 0.802 ppb, respectively. Furthermore, the mechanism of sensing CIP and OFLX was exposed to the photoinduced electron transfer (PET) and dynamic quenching process, as evaluated by DFT calculations and fluorescence lifetime decay measurements. Our work first reports a simple and efficient strategy for recognizing CIP and OFLX with a special luminescence color-change phenomenon based on MOF materials, serving as a meaningful guide for researchers in beneficial applications.
氟喹诺酮类抗生素（FQ）残留，如环丙沙星（CIP）和氧氟沙星（OFLX），由于其在环境水或食品领域的严重影响而引起了公众的关注，这些影响会影响人类健康。因此，迫切需要一种简单、高性能的用于检测 FQ 的传感方法。在此，我们提出了一种具有独特二维（4-c）{4.6}-连接拓扑结构的发光 Eu-MOF，其在水溶液中具有出色的荧光性能和优异的化学稳定性，可稳定 15 天。因此，Eu-MOF 可以被认为是一种高灵敏度的化学传感器，用于检测 CIP 和 OFLX，具有不同的荧光颜色转换（OFLX 由红色变为绿色，CIP 由红色变为蓝色），检测限分别低至 0.693 和 0.802 ppb。此外，通过 DFT 计算和荧光寿命衰减测量，揭示了 CIP 和 OFLX 的传感机制为光诱导电子转移（PET）和动态猝灭过程。我们的工作首次报道了一种基于 MOF 材料识别 CIP 和 OFLX 的简单高效策略，为研究人员在有益应用方面提供了有意义的指导。
