Department of Chemical Engineering, VNIT, Nagpur, India.
Crit Rev Biotechnol. 2021 Sep;41(6):935-952. doi: 10.1080/07388551.2021.1898329. Epub 2021 Mar 21.
Probiotics provide many beneficial effects to the human body. Traditionally, food products used to deliver bacterial cells are fermented dairy products, among which yogurt is the most common. However, many people suffer from lactose intolerance and indigestion, who need nutrients from non-dairy products without using animal proteins. Thus, there is a need to develop synbiotics based on non-dairy food matrices. This paper reviews the potential and emerging candidates of pre and probiotic groups. The criteria for qualifying bacteria as probiotics and nutrients as prebiotics are discussed. One of the promising prebiotics explored in the recent past is the dietary fibers in the peels of potato, apples, and other fruits. This paper summarizes methods for the preparation of dietary fiber-based non-dairy synbiotics such as microencapsulation, freeze-drying, and spray drying. The standard testing protocols of synbiotics including the trials are presented. Synbiotics not only favor the survival of probiotics in the gastric conditions of the human gut but also exhibit antimicrobial activity, which confirms their ability to protect the human body from infection. Many fiber-based non-dairy synbiotic products are available in the market and these are also highlighted. The challenges faced by non-dairy-based synbiotics which open up new research opportunities and market demand are also identified.
益生菌对人体有许多有益的影响。传统上，用于输送细菌细胞的食品是发酵乳制品，其中酸奶最为常见。然而，许多人患有乳糖不耐受和消化不良，他们需要非乳制品中的营养物质而不使用动物蛋白。因此，需要基于非乳制品基质开发合生元。本文综述了前体和益生菌组的潜在和新兴候选物。讨论了将细菌鉴定为益生菌和将营养素鉴定为益生元的标准。在过去的研究中，一种有前途的益生元是土豆、苹果和其他水果皮中的膳食纤维。本文总结了基于膳食纤维的非乳制品合生元的制备方法，如微胶囊化、冷冻干燥和喷雾干燥。还介绍了合生元的标准测试方案，包括临床试验。合生元不仅有利于益生菌在人体肠道的胃条件下的存活，而且还表现出抗菌活性，这证实了它们保护人体免受感染的能力。市场上有许多基于纤维的非乳制品合生元产品，也对其进行了强调。还确定了非乳制品合生元所面临的挑战，这些挑战为新的研究机会和市场需求开辟了道路。
