Department of Ophthalmology, Hospital CUF Descobertas, Lisbon, Portugal.
Department of Hematology and Oncology, CUF Oncologia, Lisbon, Portugal.
Orbit. 2022 Oct;41(5):605-610. doi: 10.1080/01676830.2021.1901293. Epub 2021 Mar 22.
Epithelial tumors of the lacrimal gland are rare and usually develop in the orbital lobe. We report the exceedingly rare occurrence of a primary adenoid cystic carcinoma in the palpebral lobe of the lacrimal gland. A 26-year-old female was referred for evaluation of a gradually enlarging mass in the lateral upper eyelid, previously diagnosed as a chalazion. Computed tomography revealed a heterogeneous round lesion anterior to the orbital rim. Excisional biopsy was compatible with an adenoid cystic carcinoma. After excluding distant metastasis, and as the patient refused adjuvant radiotherapy, a second surgical procedure, with wide local excision, was indicated. Follow-up showed no recurrence. This case highlights the importance of performing a thorough clinical examination when diagnosing any lateral upper eyelid mass. A high index of suspicion for malignant tumors of the lacrimal gland should always be maintained, and a complete excision with histological analysis should be preferred whenever possible.
泪腺上皮性肿瘤较为罕见，通常发生在眶叶。我们报告了一例极为罕见的原发于泪腺睑叶的腺样囊性癌。一名 26 岁女性因外侧上眼睑逐渐增大的肿块就诊，该肿块先前被诊断为霰粒肿。计算机断层扫描显示眶缘前有一个不均匀的圆形病变。切除活检符合腺样囊性癌。排除远处转移后，由于患者拒绝辅助放疗，故行第二次手术，广泛局部切除。随访未见复发。本例强调了在诊断任何外侧上眼睑肿块时进行彻底临床检查的重要性。当怀疑为泪腺恶性肿瘤时应始终保持高度警惕，只要有可能，应尽可能进行完整切除并进行组织学分析。
