Department of Radiology, Muğla Sıtkı Koçman University Medical Faculty, Muğla, Turkey.
Folia Morphol (Warsz). 2022;81(2):307-313. doi: 10.5603/FM.a2021.0022. Epub 2021 Mar 22.
This study aimed to reveal the change in olfactory bulbus volume (OBV) and olfactory sulcus depth (OSD) in healthy Turkish paediatric individuals between 1 month and 18 years of age with 3 Tesla magnetic resonance imaging (MRI), taking into account different age groups and gender factors.
In this retrospective study, 190 paediatric individuals who underwent cranial MRI were evaluated. Healthy paediatric cases were divided into four groups as infantile period (first 24 months when cerebral myelinisation was completed), early childhood (2-6 years), childhood (6-12 years) and adolescence (12-18 years). OBV and OSD measurements were performed on coronal T2-weighted brain MRI by 3 Tesla magnetic resonance scan. The mean, right and left OBVs and OSDs were used for evaluation.
The mean age was 9.9 ± 7.5 months for the infantile period, 4.5 ± 1.3 years for early childhood, 9.3 ± 1.7 years for childhood and 15.2 ± 1.7 years for adolescence. Mean, right and left OBV was found to be slightly larger in male children than in female children (p = 0.015, p = 0.033 and p = 0.010, respectively). There was no statistical difference between the genders for mean, right and left OSD (p = 0.559, p = 0.536 and p = 0.598, respectively). Among the age groups, the values of the 3rd and 4th groups in terms of mean, right and left OBV were higher than in the other two groups (p < 0.001). In terms of OSD, mean, right and left values were higher in group 2, 3 and 4 than in group 1 (p < 0.001).
These data differ by paediatric age group and gender for the development of OBV and OSD. Normal values for the paediatric age group and gender should be calculated to detect olfactory dysfunction.
本研究旨在通过 3 特斯拉磁共振成像（MRI），观察健康土耳其儿童个体嗅球体积（OBV）和嗅沟深度（OSD）在 1 个月至 18 岁之间的变化，同时考虑到不同的年龄组和性别因素。
在这项回顾性研究中，评估了 190 名接受颅 MRI 的儿科患者。健康儿科患者分为 4 组：婴儿期（大脑髓鞘化完成时的前 24 个月）、幼儿期（2-6 岁）、儿童期（6-12 岁）和青春期（12-18 岁）。在冠状 T2 加权脑 MRI 上通过 3 特斯拉磁共振扫描进行 OBV 和 OSD 测量。使用平均值、右侧和左侧 OBV 和 OSD 进行评估。
婴儿期的平均年龄为 9.9 ± 7.5 个月，幼儿期为 4.5 ± 1.3 岁，儿童期为 9.3 ± 1.7 岁，青春期为 15.2 ± 1.7 岁。男性儿童的平均、右侧和左侧 OBV 略大于女性儿童（p = 0.015、p = 0.033 和 p = 0.010）。性别之间的平均、右侧和左侧 OSD 无统计学差异（p = 0.559、p = 0.536 和 p = 0.598）。在年龄组中，第 3 组和第 4 组的平均值、右侧和左侧 OBV 值高于其他两组（p < 0.001）。就 OSD 而言，第 2、3 和 4 组的平均、右侧和左侧值高于第 1 组（p < 0.001）。
OBV 和 OSD 的发育因儿科年龄组和性别而异。为了检测嗅觉功能障碍，应该为儿科年龄组和性别计算正常值。
