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青少年神经性厌食症或非典型神经性厌食症及发病前超重/肥胖与饮食障碍严重程度和心理病态的关系。

Eating disorder severity and psychological morbidity in adolescents with anorexia nervosa or atypical anorexia nervosa and premorbid overweight/obesity.

机构信息

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

出版信息

Eat Weight Disord. 2022 Feb;27(1):233-242. doi: 10.1007/s40519-021-01168-7. Epub 2021 Mar 22.

Abstract

PURPOSE

A significant proportion of adolescents with anorexia nervosa (AN) or atypical anorexia nervosa (AAN) experience premorbid overweight/obesity, yet distinct characteristics among this subset of patients remain unclear. This study examined eating disorder (ED) symptom severity, psychological morbidity, and weight stigma in patients with premorbid overweight/obesity as compared to patients with premorbid normal weights.

METHODS

Participants included adolescents with AN or AAN (aged 12-18) who received multidisciplinary treatment at a pediatric medical center in the United States. ED symptoms, anxiety, and depression were compared among patients with premorbid overweight/obesity (n = 43) and premorbid normal weights (n = 63). Associations between weight stigma, ED severity, and psychological morbidity were also examined.

RESULTS

Patients with premorbid overweight/obesity reported greater ED severity (p = 0.04), anxiety (p < 0.003), depression (p = 0.02), and a higher frequency of weight-based teasing by peers (p = 0.003) and parent weight talk about their own weights (p < 0.001). Weight-based teasing was positively associated with ED symptoms, anxiety, and depression for all patients, regardless of premorbid weight status.

CONCLUSIONS

Adolescents with AN or AAN and a history of overweight/obesity may present with greater ED symptom severity and psychological morbidity than patients with normal weight histories. Distinct prevention and treatment interventions for adolescents with AN or AAN and premorbid overweight/obesity may be warranted.

LEVEL OF EVIDENCE

Level III, case-control analytic study.

摘要

目的

相当一部分神经性厌食症(AN)或非典型神经性厌食症(AAN)患者在发病前存在超重/肥胖,但这部分患者的特征仍不清楚。本研究比较了发病前超重/肥胖患者与发病前体重正常患者的饮食障碍(ED)症状严重程度、心理发病率和体重耻辱感。

方法

参与者包括在美国一家儿科医疗中心接受多学科治疗的 AN 或 AAN 青少年(年龄 12-18 岁)。比较了发病前超重/肥胖(n=43)和发病前体重正常(n=63)患者的 ED 症状、焦虑和抑郁。还检查了体重耻辱感、ED 严重程度和心理发病率之间的关联。

结果

发病前超重/肥胖的患者报告 ED 严重程度更高(p=0.04),焦虑(p<0.003),抑郁(p=0.02),以及同伴基于体重的嘲笑(p=0.003)和父母谈论自己体重的频率更高(p<0.001)。对于所有患者,无论发病前体重状况如何,基于体重的嘲笑与 ED 症状、焦虑和抑郁均呈正相关。

结论

有超重/肥胖病史的 AN 或 AAN 青少年患者可能比有正常体重病史的患者表现出更严重的 ED 症状和心理发病率。对于有 AN 或 AAN 及发病前超重/肥胖病史的青少年,可能需要进行特定的预防和治疗干预。

证据水平

三级,病例对照分析研究。

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