Skácelová Martina, Horák Pavel, Janková Jana
Vnitr Lek. 2021 Winter;67(1):58-61.
Incidence of ANCA antibodies in patients with systemic lupus erythematosus (SLE) is described in 24-31 %, but they are not related to the distribution and severity of organ involvement in SLE; the routine monitoring is not recommended. Overlap syndrome of systemic lupus erythematosus and ANCA associated vasculitis (AAV) is rare. The difficult diagnosis and treatment of this syndrome is described in this case report of the patient with SLE and severe kidney involvement resulting from AAV.
系统性红斑狼疮（SLE）患者中抗中性粒细胞胞浆抗体（ANCA）的发生率为24% - 31%，但它们与SLE中器官受累的分布和严重程度无关；不建议进行常规监测。系统性红斑狼疮与ANCA相关血管炎（AAV）的重叠综合征很罕见。本病例报告描述了一名患有SLE且因AAV导致严重肾脏受累的患者，该综合征的诊断和治疗颇具难度。
