Mitrovic Jovanovic Milica, Djuric-Stefanovic Aleksandra, Velickovic Dejan, Keramatollah Ebrahimi, Micev Marijan, Jankovic Aleksandra, Milosevic Stefan, D Kovac Jelena
Centre for Radiology and MRI, University Clinical Centre of Serbia, Belgrade, Serbia.
Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
J Int Med Res. 2021 Mar;49(3):300060521994927. doi: 10.1177/0300060521994927.
Aggressive fibromatosis is a rare type of intra-abdominal desmoid tumour that usually involves the small bowel mesentery. It is a locally-invasive lesion, with a high rate of recurrence, but without metastatic potential. Aggressive fibromatosis is seen more often in young female patients. This case report presents the radiological, intraoperative and histopathological findings from a 37-year-old female patient that presented with epigastric pain and a palpable mass in the right hemiabdomen. Histological and immunohistochemical examinations of the resected tumour, including positive staining for beta-catenin, confirmed a postoperative diagnosis of desmoid type fibromatosis. This specific case showed that desmoid type fibromatosis of the colon can mimic gastrointestinal stromal tumours (GIST) based on its clinical presentation, computed tomography and magnetic resonance imaging findings. Differential diagnosis between desmoid type fibromatosis and GIST is clinically very important due to the different treatments and follow-up protocols that are implemented for these lesions.
侵袭性纤维瘤病是一种罕见的腹腔内硬纤维瘤，通常累及小肠系膜。它是一种局部侵袭性病变，复发率高，但无转移潜能。侵袭性纤维瘤病在年轻女性患者中更为常见。本病例报告展示了一名37岁女性患者的影像学、术中及组织病理学检查结果，该患者表现为上腹部疼痛且右半腹可触及肿块。对切除肿瘤进行的组织学和免疫组化检查，包括β-连环蛋白阳性染色，确诊为术后硬纤维瘤型纤维瘤病。这个特殊病例表明，结肠硬纤维瘤型纤维瘤病基于其临床表现、计算机断层扫描和磁共振成像结果可酷似胃肠道间质瘤（GIST）。由于对这些病变实施的治疗和随访方案不同，硬纤维瘤型纤维瘤病与GIST之间的鉴别诊断在临床上非常重要。
