Surgical Oncology, Ruby Hall Clinic, Pune, Maharashtra, India.
Medical Oncology, Ruby Hall Clinic, Pune, Maharashtra, India.
Indian J Cancer. 2021 Apr-Jun;58(2):267-272. doi: 10.4103/ijc.IJC_705_19.
We herein describe a case of primary leiomyosarcoma of descending mesocolon mesentery in a pregnant woman. A 31-year-old woman was referred to our clinic for the presence of a suspicious mass (solid heterogenous lesion with lobulated margins) detected during routine obstetric ultrasonography (USG), growing throughout her term. Imaging in her third trimester showed a considerable increase in the size of the mass and was suspected to be malignancy of uterine origin. Tru-cut biopsy performed post-partum indicated leiomyosarcoma. She underwent neoadjuvant chemotherapy with six cycles of dacarbazine and doxorubicin with partial response. Subsequently, she underwent surgery, and the tumor was found to be present in sigmoid colon mesentery extending in retroperitoneum involving 5 cm of ureter. The mass was resected along with part of the colon and ureter that was involved by disease. Patient had uneventful recovery post-surgery. Considering moderate response to chemotherapy and discussion in tumor board, she was not given adjuvant chemotherapy. At follow-up of 15 months, the patient is disease-free with a normal, healthy baby.
我们在此描述了一例妊娠女性降结肠系膜原发性平滑肌肉瘤病例。一名 31 岁女性因例行产科超声检查（USG）发现疑似肿块（边界分叶状的实性混杂性病变）而就诊于我科，该肿块在整个孕期持续生长。她孕晚期的影像学检查显示肿块大小明显增大，疑似子宫来源的恶性肿瘤。产后行 Tru-cut 活检提示平滑肌肉瘤。她接受了六个周期的达卡巴嗪和顺铂新辅助化疗，部分缓解。随后，她接受了手术，发现肿瘤位于乙状结肠系膜，延伸至腹膜后，累及 5 厘米输尿管。肿块与受累部分结肠和输尿管一起被切除。患者术后恢复顺利。鉴于化疗的中度反应和肿瘤委员会的讨论，她未接受辅助化疗。随访 15 个月时，患者无疾病，且有一个正常、健康的婴儿。
