Department of Ophthalmology, Korea University, College of Medicine, Korea University Guro Hospital, 148, Gurodong-ro, Guro-gu, Seoul, 08308, Republic of Korea.
Sci Rep. 2021 Mar 22;11(1):6484. doi: 10.1038/s41598-021-86004-9.
We investigated the period of postoperative exodrift during follow-up and clinical factors that affect the rate of exodrift after surgery in the patients with intermittent exotropia (IXT). A retrospective review of medical records of patients with exodrift who underwent bilateral rectus recession for IXT was performed. Exodrift was defined as angle of deviation greater than 10 prism diopters (PD) at distance and near. The median survival period of postoperative exodrift was analyzed using Kaplan Meier survival analysis. The patients were divided into two groups according to the median period of postoperative exodrift (early and late group). The weighted Cox's proportional hazards regression analysis to investigate the risk factors that affect rate of postoperative exodrift was performed. A total of 108 patients was included. The preoperative angle of deviation at distance and near were 30.3 ± 7.2 PD and 29.5 ± 8.6 PD, respectively. The median survival period of postoperative exodrift was 24 months (range, 6-48 months).The angle of deviation at postoperative day 1 in early and late group were - 3.8 ± 5.5 PD (range, - 16-8 PD) and - 7.7 ± 4.6 PD (range, - 16-4 PD) (p < 0.01). Minus value means esodeviation. In regression analysis, the angle of deviation at postoperative day 1 was the significantly related with rate of exodrift (p < 0.01). The median period of exodrift after surgery was 24 months, angle of deviation at postoperative day 1 could affect the rate of exodrift in patients with IXT.
我们研究了间歇性外斜视（IXT）患者手术后外斜视漂移的随访期以及影响术后外斜视漂移率的临床因素。对接受双侧直肌后退术治疗外斜视漂移的患者的病历进行了回顾性分析。外斜视漂移定义为在远距离和近距离时，斜视角度大于 10 棱镜度（PD）。使用 Kaplan-Meier 生存分析分析术后外斜视漂移的中位生存时间。根据术后外斜视漂移的中位时间（早期和晚期组）将患者分为两组。使用加权 Cox 比例风险回归分析来研究影响术后外斜视漂移率的危险因素。共纳入 108 例患者。术前远距离和近距离斜视角度分别为 30.3±7.2 PD 和 29.5±8.6 PD。术后外斜视漂移的中位生存时间为 24 个月（范围为 6-48 个月）。早期和晚期组术后第 1 天的斜视角度分别为-3.8±5.5 PD（范围为-16-8 PD）和-7.7±4.6 PD（范围为-16-4 PD）（p<0.01）。负数表示内斜视。在回归分析中，术后第 1 天的斜视角度与外斜视漂移率显著相关（p<0.01）。术后外斜视漂移的中位时间为 24 个月，术后第 1 天的斜视角度可影响 IXT 患者的外斜视漂移率。
