Velasco de Cos Guillermo, Sánchez-Molina Acosta María Isabel, Fernández María Matilde Toval
Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Hospital Comarcal de Laredo, Spain.
EJIFCC. 2021 Feb 28;32(1):105-110. eCollection 2021 Feb.
Euglycemic diabetic ketoacidosis (euglycemic DKA) is a serious complication of diabetes, which can occur in some patients treated with oral antidiabetics called sodium-glucose co-transporter 2 inhibitors (SGLT2i). This group of drugs works by increasing renal excretion of sodium and glucose, thereby lowering blood glucose levels. Euglycemic DKA is characterized by having blood glucose levels in the normal range, usually below 200 mg/dL (11 mmol/L), which complicates early diagnosis. We present the case of a 67-year-old patient with type 2 diabetes mellitus, treated with metformin and empagliflozin, who was admitted to the Intensive Care Unit in a coma with severe ketoacidotic decompensation.
正常血糖性糖尿病酮症酸中毒(正常血糖性DKA)是糖尿病的一种严重并发症,可发生于一些使用名为钠-葡萄糖协同转运蛋白2抑制剂(SGLT2i)的口服抗糖尿病药物治疗的患者中。这类药物通过增加肾脏对钠和葡萄糖的排泄起作用,从而降低血糖水平。正常血糖性DKA的特征是血糖水平在正常范围内,通常低于200mg/dL(11mmol/L),这使得早期诊断变得复杂。我们报告一例67岁2型糖尿病患者的病例,该患者接受二甲双胍和恩格列净治疗,因严重酮症酸中毒失代偿昏迷入住重症监护病房。