一例罕见的因恩格列净诱发的正常血糖性糖尿病酮症酸中毒被碱中毒掩盖的病例。
A Rare Case of Empagliflozin-Induced Euglycemic Diabetic Ketoacidosis Obscured by Alkalosis.
作者信息
Fernandez Felix Daniel A, Madrigal Loria Gloriana, Sharma Sapna, Sharma Shorabh, Arias Morales Carlos E
机构信息
Medicine, St. Barnabas Hospital (SBH) Health System, Bronx, USA.
Clinical Medicine, Sophie Davis School of Medicine, City University of New York, Bronx, USA.
出版信息
Cureus. 2022 Jun 10;14(6):e25818. doi: 10.7759/cureus.25818. eCollection 2022 Jun.
Abstract
Empagliflozin-induced euglycemic diabetic ketoacidosis is a life-threatening metabolic complication of diabetes mellitus characterized by metabolic acidosis, ketonemia, and relatively normal serum glucose levels. We present a rare case of empagliflozin-induced diabetic ketoacidosis obscured by alkalosis. This case report aims to create awareness among clinicians about this entity and consider this diagnosis in their differential, especially in patients taking sodium-glucose co-transporter (SGLT-2) inhibitors who present to the hospital with unspecific symptoms that may not suggest DKA.
摘要
恩格列净诱导的正常血糖性糖尿病酮症酸中毒是糖尿病的一种危及生命的代谢并发症，其特征为代谢性酸中毒、酮血症和相对正常的血清葡萄糖水平。我们报告一例罕见的因碱中毒掩盖而导致的恩格列净诱导的糖尿病酮症酸中毒病例。本病例报告旨在提高临床医生对该疾病的认识，并在鉴别诊断时考虑这一诊断，尤其是对于那些服用钠-葡萄糖协同转运蛋白（SGLT-2）抑制剂且因非特异性症状入院但这些症状可能不提示糖尿病酮症酸中毒的患者。
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