首次从巴基斯坦第二波疫情中记录到 SARS-COV-2 的再感染。

First documented reinfection of SARS-COV-2 in second wave from Pakistan.

机构信息

Institute of Public Health, Khyber Medical University, Peshawar, Pakistan.

Department of Medicine, MTI Hayatabad Medical Complex, Peshawar, Pakistan.

出版信息

J Ayub Med Coll Abbottabad. 2020 Oct-Dec;32(Suppl 1)(4):S704-S705.

Abstract

Little is known about the pathophysiology and immunology of Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2). It is not yet clear whether SARS-CoV-2 infection produces long-term immune protection, or a short-lived immunity that would fade with the passage of time. We report a first case of SARS-CoV-2 reinfection in second wave from Pakistan. A 41-year-old male, health care worker developed flu-like illness, tested positive on 6th June 2020 and became PCR negative on 19th June 2020 with reactive antibodies. After 4 months and 13 days of negative PCR, he developed symptoms again and tested positive for SARS-CoV-2 with non-reactive antibodies.

摘要

目前对于严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的发病机制和免疫学了解甚少。目前尚不清楚 SARS-CoV-2 感染是否产生长期免疫保护，还是随着时间的推移会逐渐消失的短暂免疫。我们报告了首例来自巴基斯坦第二波 SARS-CoV-2 再感染病例。一名 41 岁男性，医护工作者，出现流感样症状，于 2020 年 6 月 6 日检测出阳性，2020 年 6 月 19 日 PCR 转为阴性，同时伴有抗体反应。在 PCR 连续 4 个月 13 天阴性后，他再次出现症状，并检测出 SARS-CoV-2 阳性，且抗体无反应。