Miyatake H, Saito K, Kurihara N
Radioisotope Research Center, Kyoto University, Japan.
Radioisotopes. 1988 Jan;37(1):27-30. doi: 10.3769/radioisotopes.37.27.
Mice were dry-distilled at 800 degrees C for 10 min, after [32P]orthophosphate or L-[4,5-3H]leucine was intraperitoneally administered. Phosphorus-32 was quantitatively recovered in the residual solid, whereas 95% of 3H was found int he distillate (condensed water). When 14C (L-[U-14C]malic acid or L-[U-14C]leucine) was administered to mice and they were dry-distilled, 14C-radioactivity was distributed into two fractions; residual solid and exhaust gas. In these cases, the recovery percentage of 14C in residual solid was not very high but increased as the treating temperature decreased. It reached about 40% of the administered 14C at 400 degrees C for 120 min. By the dry-distillation of animals, their weight was reduced to about 10% in every animal tested (mice, rats and rabbits). The volume was reduced to about 20% in cases of mice and rats, and about 30% in case of rabbits. It was concluded that the dry-distillation can be useful as a pre-treatment for disposal of animal wastes containing radioisotopes.
在腹腔注射[32P]正磷酸盐或L-[4,5-3H]亮氨酸后，将小鼠在800℃下进行干馏10分钟。磷-32定量回收在残余固体中，而95%的3H存在于馏出物（冷凝水）中。当给小鼠注射14C（L-[U-14C]苹果酸或L-[U-14C]亮氨酸）并进行干馏时，14C放射性分布在两个部分：残余固体和废气中。在这些情况下，残余固体中14C的回收率不是很高，但随着处理温度的降低而增加。在400℃下处理120分钟时，其达到所注射14C的约40%。通过对动物进行干馏，每只受试动物（小鼠、大鼠和兔子）的体重减轻至约10%。小鼠和大鼠的体积减少至约20%，兔子的体积减少至约30%。得出的结论是，干馏可作为处理含放射性同位素动物废物的预处理方法。
