Emerg Infect Dis. 2021;27(4):1173-1176. doi: 10.3201/eid2704.202400.
During the 2019 Eastern equine encephalitis virus (EEEV) outbreak in Michigan, two 2-month old Mexican wolf pups experienced neurologic signs, lymphohistiocytic neutrophilic meningoencephalitis with neuronal necrosis and neuronophagia, and acute death. We identified EEEV by reverse transcription real-time PCR and in situ hybridization. Vector mosquitoes were trapped at the zoo.
在 2019 年密歇根东部马脑炎病毒(EEEV)爆发期间,两只 2 个月大的墨西哥狼幼崽出现了神经症状,表现为淋巴组织细胞性中性粒细胞性脑膜脑炎伴神经元坏死和噬神经现象,并且迅速死亡。我们通过反转录实时 PCR 和原位杂交技术鉴定出了 EEEV。在动物园里捕获了携带病毒的蚊子。