Emerg Infect Dis. 2021 Apr;27(4):1133-1140. doi: 10.3201/eid2704.202337.
Campylobacteriosis is a disease of worldwide importance, but aspects of its transmission dynamics, particularly risk factors, are still poorly understood. We used data from a matched case-control study of 4,269 men who have sex with men (MSM) and 26,215 controls, combined with national surveillance data on Campylobacter spp., Salmonella spp., and Shigella spp., to calculate matched odds ratios (mORs) for infection among MSM and controls. MSM had higher odds of Campylobacter (mOR 14, 95% CI 10-21) and Shigella (mOR 74, 95% CI 27-203) infections, but not Salmonella (mOR 0.2, 95% CI 0-13), and were less likely than controls to have acquired Campylobacter infection abroad (χ = 21; p<0.001). Our results confirm that sexual contact is a risk factor for campylobacteriosis and also suggest explanations for unique features of Campylobacter epidemiology. These findings provide a baseline for updating infection risk guidelines to the general population.
弯曲菌病是一种具有全球重要性的疾病，但它的传播动力学的各个方面，特别是危险因素，仍未被充分了解。我们使用了一项针对 4269 名男男性行为者 (MSM) 和 26215 名对照的匹配病例对照研究的数据，结合国家对弯曲菌属、沙门氏菌属和志贺氏菌属的监测数据，计算了 MSM 和对照组之间感染的匹配比值比 (mOR)。MSM 感染弯曲菌 (mOR 14, 95% CI 10-21) 和志贺菌 (mOR 74, 95% CI 27-203) 的几率更高，但感染沙门氏菌的几率较低 (mOR 0.2, 95% CI 0-13) ，而且与对照组相比，他们在国外感染弯曲菌的可能性较小 (χ=21; p<0.001)。我们的研究结果证实，性接触是弯曲菌病的一个危险因素，同时也为弯曲菌病流行病学的独特特征提供了一些解释。这些发现为更新一般人群的感染风险指南提供了基线数据。
