Perez-Carpena Patricia, Lopez-Escamez Jose A
Otology & Neurotology Group CTS495, Department of Genomic Medicine, GENYO-Centre for Genomics and Oncological Research - Pfizer/University of Granada/Junta De Andalucía, Granada, PTS, Spain.
Department of Otolaryngology, Instituto De Investigación Biosanitaria ibs.GRANADA, Hospital Universitario Virgen De Las Nieves, Granada, Spain.
Expert Rev Neurother. 2021 May;21(5):503-516. doi: 10.1080/14737175.2021.1908129. Epub 2021 Apr 6.
: Vestibular migraine (VM) is a complex disease characterized by recurrent episodes of migraine associated with vertigo attacks that are observed in 1-3% of the general population. Given its high prevalence and the impact on the health system, it is important to characterize these patients, in order to offer an accurate diagnosis and a proper treatment. As the diagnosis of VM is based on clinical features, the study of potential biomarkers has gained more interest in the last years, to improve the precision in the diagnosis of this disease. The aim of this review is to summarize the main tests available for the diagnosis of VM, including the accuracy of biomarkers for the diagnosis of VM.: This review summarizes the main information on VM, including all diagnosis records published in the field in the last 10 years, and focusing on candidate biomarkers for the diagnosis of VM patients.: There is a limited knowledge in the pathophysiology of VM. The search of biomarkers for diagnosis of VM is needed to improve the precision in the diagnosis promoting clinical and translational research. The potential reclassification of VM will depend upon the discovery and validation of these biomarkers.
前庭性偏头痛(VM)是一种复杂的疾病,其特征为偏头痛反复发作并伴有眩晕发作,在普通人群中的发病率为1%至3%。鉴于其高患病率以及对卫生系统的影响,对这些患者进行特征描述很重要,以便提供准确的诊断和恰当的治疗。由于VM的诊断基于临床特征,近年来对潜在生物标志物的研究更受关注,以提高该疾病诊断的准确性。本综述的目的是总结可用于VM诊断的主要检测方法,包括VM诊断生物标志物的准确性。:本综述总结了关于VM的主要信息,包括过去10年该领域发表的所有诊断记录,并重点关注VM患者诊断的候选生物标志物。:VM的病理生理学知识有限。需要寻找用于VM诊断的生物标志物,以提高诊断的准确性,促进临床和转化研究。VM的潜在重新分类将取决于这些生物标志物的发现和验证。